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胎盘疟疾的诊断

Diagnosis of placental malaria.

作者信息

Mockenhaupt Frank P, Ulmen Ulrike, von Gaertner Christiane, Bedu-Addo George, Bienzle Ulrich

机构信息

Institute of Tropical Medicine, Charité, Humboldt University, Berlin, Germany.

出版信息

J Clin Microbiol. 2002 Jan;40(1):306-8. doi: 10.1128/JCM.40.1.306-308.2002.

DOI:10.1128/JCM.40.1.306-308.2002
PMID:11773140
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC120131/
Abstract

In a group of 596 delivering Ghanaian women, the sensitivities of peripheral blood thick film microscopy, ICT Malaria P.f/P.v test, and PCR in detecting microscopically confirmed placental Plasmodium falciparum infection were 42, 80, and 97%, respectively. In addition to the gross underestimation of placental malaria by peripheral blood film microscopy, submicroscopic infections were found to be a risk factor for maternal anemia.

摘要

在一组596名分娩的加纳妇女中，外周血厚涂片显微镜检查、ICT疟原虫/间日疟原虫检测以及PCR检测显微镜确诊的胎盘恶性疟原虫感染的敏感度分别为42%、80%和97%。除了外周血涂片显微镜检查对胎盘疟疾的严重低估外，亚显微镜感染被发现是孕产妇贫血的一个危险因素。

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本文引用的文献

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The impact of placental malaria on gestational age and birth weight.胎盘疟疾对孕周和出生体重的影响。
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Submicroscopic Plasmodium falciparum infections in pregnancy in Ghana.加纳孕期的恶性疟原虫亚显微感染
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Detection of the Plasmodium falciparum antigen histidine-rich protein 2 in blood of pregnant women: implications for diagnosing placental malaria.孕妇血液中恶性疟原虫富含组氨酸蛋白2的检测：对诊断胎盘疟疾的意义
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