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上鼓室前胆脂瘤的治疗:上鼓室入路及外耳道后壁重建后的预期效果

Management of anterior epitympanic cholesteatoma: expectations after epitympanic approach and canal wall reconstruction.

作者信息

Duckert Larry G, Makielski Kathleen H, Helms Jan

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, Washington 98195-7923, USA.

出版信息

Otol Neurotol. 2002 Jan;23(1):8-13. doi: 10.1097/00129492-200201000-00003.

Abstract

BACKGROUND

The epitympanic approach to cholesteatoma provides excellent access to the anterior epitympanic space. When it is combined with reconstruction of the scutum, it is tempting to propose that the approach may offer the patient the advantage of both canal wall up and canal wall down techniques and the disadvantages of neither. In theory, then, the incidence of residual/recurrent cholesteatoma should be no greater than that for canal wall down surgery, and the need for a second look often associated with the canal wall up procedure should be less compelling. However, validation of this theory is lacking.

OBJECTIVE

To test this theory, we sought to establish the incidence of recidivism in patients undergoing cholesteatoma removal via the epitympanic approach followed by canal wall reconstruction, to identify anatomic factors predisposing to persistent disease, and to identify technical features or problems associated with recurrent cholesteatoma.

STUDY DESIGN

A retrospective case series.

SETTING

A tertiary referral center.

PATIENTS

Fifty-four adults and 11 children with extensive cholesteatoma involving but not limited to the anterior epitympanic space.

INTERVENTION

All patents underwent removal of cholesteatoma via the epitympanic approach with canal wall reconstruction followed by reexploration 1 year later.

RESULTS

Recurrent/residual disease was observed in 6 adults (11%) and 5 of 11 children (45%). The anterior epitympanic space harbored cholesteatoma in 100% of adults and 80% of children with recurrent disease.

CONCLUSION

The epitympanic approach does not eliminate the need for reexploration in cases of extensive cholesteatoma involving the anterior epitympanic space. The anterior epitympanic space is highly likely to harbor residual disease. Features of the canal wall reconstruction can be identified that predispose to recurrence. Long-term follow-up and close surveillance are mandatory, especially in children.

摘要

背景

上鼓室入路治疗胆脂瘤可很好地显露上鼓室前间隙。当该入路联合盾板重建时,有人认为此方法可为患者带来外耳道壁上翻术和外耳道壁下翻术的优点,而无两者的缺点。理论上,残余/复发性胆脂瘤的发生率应不高于外耳道壁下翻术,且通常与外耳道壁上翻术相关的二次探查需求应不那么迫切。然而,这一理论缺乏验证。

目的

为验证这一理论,我们试图确定经上鼓室入路切除胆脂瘤并进行外耳道壁重建的患者的复发率,识别易导致疾病残留的解剖因素,以及识别与复发性胆脂瘤相关的技术特点或问题。

研究设计

一项回顾性病例系列研究。

研究地点

一家三级转诊中心。

患者

54名成人和11名儿童,患有广泛的胆脂瘤,累及但不限于上鼓室前间隙。

干预措施

所有患者均经上鼓室入路切除胆脂瘤并进行外耳道壁重建,1年后再次探查。

结果

6名成人(11%)和11名儿童中的5名(45%)出现复发/残留疾病。复发疾病的成人患者中100%以及儿童患者中80%的上鼓室前间隙存在胆脂瘤。

结论

对于累及上鼓室前间隙的广泛胆脂瘤病例,上鼓室入路并不能消除二次探查的必要性。上鼓室前间隙极有可能存在残留疾病。可以确定外耳道壁重建的一些特点易导致复发。必须进行长期随访和密切监测,尤其是对儿童患者。

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