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成人经耳道上鼓室切开术一期治疗上鼓室和中鼓室胆脂瘤

Management of epi- and mesotympanic cholesteatomas by one-stage trans-canal atticotomy in adults.

作者信息

Bernardeschi Daniele, Russo Francesca Yoshie, Nguyen Yann, Canu Giuseppina, Mosnier Isabelle, De Seta Daniele, Ferrary Evelyne, Sterkers Olivier

机构信息

Department of Otology, Auditory Implants and Skull Base Surgery, AP-HP, Pitié-Salpêtrière Hospital, 50/52 Bd Vincent Auriol, 75013, Paris, France.

Sorbonne University, UPMC Univ Paris 06, 75005, Paris, France.

出版信息

Eur Arch Otorhinolaryngol. 2016 Oct;273(10):2941-6. doi: 10.1007/s00405-015-3875-3. Epub 2016 Jan 4.

Abstract

Surgical management of cholesteatoma limited to the attic and/or mesotympanum remains controversial. The aim of this study is to evaluate the anatomical and the functional results of trans-canal atticotomy in this pathological condition. The records of 27 adult patients treated from 2008 to 2014 who underwent trans-canal atticotomy for primary cholesteatoma surgery were reviewed. Pre-operative physical examination, audiometry, and CT-scan have been analyzed. Intraoperative findings have been described as well as the surgical technique. Anatomical and functional results have been evaluated with a mean follow-up of 24 ± 12.2 months, and the results of a CT-scan performed 1 year after surgery were examined to assess the presence of residual disease. Surgeries were uneventful. During the follow-up, 1 patient (4 %) experienced a retraction of the attical reconstruction; all the other patients had a well-healed tympanic drum with stable attical reconstruction. The mean air-bone gap was 19 ± 12.2 and 10 ± 7.3 dB pre-operatively and post-operatively, respectively (mean ± SD, p = 0.001, paired t test). Twenty-two patients (81 %) had no opacity suggesting residual cholesteatoma in CT-scan. Four patients (15 %) presenting an opacity at CT-scan underwent MRI study that was negative for residual cholesteatoma. One patient (4 %) had displacement of the ossicular prosthesis. In conclusion, cholesteatomas restricted to the attic and/or mesotympanum can be removed in a one-stage technique with no visible residual at 1 year, and with closure of the air-bone gap by 50 %.

摘要

仅局限于上鼓室和/或中鼓室的胆脂瘤的外科治疗仍存在争议。本研究的目的是评估在这种病理状况下经耳道上鼓室切开术的解剖学和功能结果。回顾了2008年至2014年接受经耳道上鼓室切开术进行原发性胆脂瘤手术的27例成年患者的记录。分析了术前体格检查、听力测定和CT扫描结果。描述了术中发现以及手术技术。平均随访24±12.2个月后评估了解剖学和功能结果,并检查了术后1年进行的CT扫描结果以评估残留疾病的存在。手术过程顺利。在随访期间,1例患者(4%)出现上鼓室重建回缩;所有其他患者鼓膜愈合良好,上鼓室重建稳定。术前和术后平均气骨导差分别为19±12.2 dB和10±7.3 dB(平均值±标准差,p = 0.001,配对t检验)。22例患者(81%)在CT扫描中没有提示残留胆脂瘤的不透明影。4例在CT扫描中出现不透明影的患者接受了MRI检查,结果显示无残留胆脂瘤。1例患者(4%)出现听骨假体移位。总之,局限于上鼓室和/或中鼓室的胆脂瘤可以通过一期技术切除,术后1年无可见残留,气骨导差缩小50%。

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