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喉下副神经节复发性副神经节瘤:病例报告及文献复习

Relapsing paraganglioma of the inferior laryngeal paraganglion: case report and review of the literature.

作者信息

Hinojar Adolfo G, Prieto Juan Ramón, Muñoz Elia, Hinojar Adolfo A

机构信息

Department of Otorhinolaryngology, La Princesa Hospital, Autonomous University, Diego de León 62, Madrid 28006, Spain.

出版信息

Head Neck. 2002 Jan;24(1):95-102. doi: 10.1002/hed.1156.

Abstract

BACKGROUND

Laryngeal paragangliomas are very rare neoplasms derived from the superior or inferior laryngeal paraganglia. The paragangliomas of the inferior laryngeal paraganglion, depending on their anatomic variability, can give rise to two different clinical expressions of the same process, namely the so-called thyroid paragangliomas and the inferior laryngeal or subglottic paragangliomas.

METHODS

We present a case for which we have not found any previous descriptions of a cervical and subglottictracheal relapse of a thyroid paraganglioma removed 3 years earlier. We review the literature.

RESULTS

We have found a total of 22 paragangliomas of the inferior laryngeal paraganglia, 23 including our case.

CONCLUSIONS

Thyroid paragangliomas and inferior laryngeal or subglottic paragangliomas should be included under the term "paragangliomas" of the inferior laryngeal paraganglion. These tumors are slow growing, benign, hypervascular, and much more common in middle-aged women. Immunohistochemistry is essential for its diagnosis. Open, conservative surgery is the treatment of choice.

摘要

背景

喉副神经节瘤是源自喉上或喉下副神经节的非常罕见的肿瘤。喉下副神经节的副神经节瘤,根据其解剖变异,可导致同一病程的两种不同临床表现,即所谓的甲状腺副神经节瘤和喉下或声门下副神经节瘤。

方法

我们报告一例3年前切除的甲状腺副神经节瘤出现颈部和声门下气管复发的病例,此前未发现相关描述。我们回顾了文献。

结果

我们共发现22例喉下副神经节的副神经节瘤,包括我们的病例在内共23例。

结论

甲状腺副神经节瘤和喉下或声门下副神经节瘤应归入喉下副神经节的“副神经节瘤”这一术语。这些肿瘤生长缓慢、为良性、血管丰富,在中年女性中更为常见。免疫组织化学对其诊断至关重要。开放性保守手术是首选治疗方法。

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