Zhao S, Wang S, Yan J
Department of Stomatology, Second Affiliated Hospital of Zhejiang Medical University, Hangzhou 310031.
Zhonghua Kou Qiang Yi Xue Za Zhi. 1998 Nov;33(6):353-4.
To compare the diference of the bone formation between immediate and delayed implantation, and evaluate the role of the hydroxyapatite (HA) in immediate implantation.
HA coated titanium implants were implanted into the femurs of adult dogs, the diameter of the socket was 6.5 mm and 3.5 mm respectively, HA coated titanium implants (all with the diameter of 3.5 mm) were placed into the latter sockets, and was considered to be the model of delayed implantation. The implantation in the 6.5 mm socket were considered to be the model of immediate implantation. The immediate implantation was divided into two groups, HA granules were filled in between the bone and implant in one group, and no HA particles was filled in another group. Animals were killed at 1,2,3 and 4 months post operation.
Immature new bone formation was found on all specimens one month after implantation, and the amount of new bone formation in HA particles filled group was much more than that group without HA particles. In the HA granules group, there was no marked difference from the group of implantation in 3.5 mm socket. Mature new bone was observed four months later after operation, and no marked difference was found in the amount of new bone between HA granules filled implantation in 6.5 mm socked and implantation in 3.5 mm socket.
Implantation of HA granules is helpful to the stability of the implant and plays a role in the healing of implant with surrounding bones.
比较即刻种植与延期种植骨形成的差异，评价羟基磷灰石（HA）在即刻种植中的作用。
将HA涂层钛种植体植入成年犬股骨，牙槽窝直径分别为6.5mm和3.5mm，将HA涂层钛种植体（直径均为3.5mm）植入后者牙槽窝，视为延期种植模型。将种植于6.5mm牙槽窝的视为即刻种植模型。即刻种植分为两组，一组在骨与种植体之间填充HA颗粒，另一组不填充HA颗粒。术后1、2、3和4个月处死动物。
植入后1个月，所有标本均见未成熟新骨形成，HA颗粒填充组新骨形成量明显多于未填充HA颗粒组。HA颗粒组与植入3.5mm牙槽窝组无明显差异。术后4个月观察到成熟新骨，6.5mm牙槽窝HA颗粒填充种植与3.5mm牙槽窝种植新骨量无明显差异。
HA颗粒植入有助于种植体的稳定性，对种植体与周围骨的愈合起作用。
