Bao Xiangjun, Liang Xing, Li Xinghong, Gao Weimin
Department of Prosthetics, West China School of Stomatology, Sichuan University, Chengdu 610041, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2003 Apr;34(2):267-9.
To evaluate the titanium membrane-guided bone tissue regeneration around implant and HA granules.
Three adult cross-bred dogs were used. In the animal's mandible, man-made bone damaged regions (diameter 6.5 mm, depth 4 mm) being concentric with the implant holes were prepared. The implants were planted into the holes and were rendered to separate the damaged regions into two parts with two titanium sheets. One part was filled with HA granules while the other with nothing. Histological evaluation was done at 4, 8 and 12 weeks of implantation.
The bone around the implants grew obviously at 4 weeks; the bone grew more and the structure of the bone was similar to that of the normal bone at 12 weeks.
As a new type of GTR materials, titanium membrane can keep the existence of spaces underneath. HA granules can give guiding effects to bone tissue regeneration.
评估钛膜引导种植体周围及羟基磷灰石颗粒周围骨组织再生情况。
选用3只成年杂交犬。在动物下颌骨制备与种植体孔同心的人为骨损伤区域（直径6.5毫米，深度4毫米）。将种植体植入孔内，并用两片钛片将损伤区域分隔为两部分。一部分填充羟基磷灰石颗粒，另一部分不填充。在植入后4周、8周和12周进行组织学评估。
植入后4周种植体周围骨明显生长；12周时骨生长更多且骨结构与正常骨相似。
作为一种新型引导组织再生材料，钛膜可保持下方空间的存在。羟基磷灰石颗粒可对骨组织再生起到引导作用。
