[中医药治疗对口腔扁平苔藓患者的免疫调节作用]
[Immunoregulation effect of traditional Chinese medicine treatment on patients with oral lichen planus].
作者信息
Pang J, Bu J
机构信息
Department of Stomatology, General Hospital of PLA, Beijing 100853.
出版信息
Zhonghua Kou Qiang Yi Xue Za Zhi. 1998 Jan;33(1):48-9.
OBJECTIVE
To explore effect of traditional Chinese medicine (TCM) treatment on immune state of patients with oral lichen planus (OLP).
METHODS
30 cases of patients with OLP were treated by TCM and peripheral blood T-lymphocyte subgroup in these patients were determined.
RESULTS
CD3, CD4 and CD4/CD3 ratio of patients with OLP were decreased significantly, compared with that of health people (P < 0.01) before TCM treatment, while after TCM treatment CD3, CD4 and CD4/CD3 ratio were increased significantly (P < 0.01) and the latter recovered to normal, 8 patients recovered, 14 cases significantly improved, and 8 cases improved.
CONCLUSION
TCM therapy is useful for the treatment of OLP. It acts biphasically a regulation effect on the immunologic balance of the patient.
目的
探讨中医治疗对口腔扁平苔藓（OLP）患者免疫状态的影响。
方法
对30例OLP患者进行中医治疗，并检测这些患者外周血T淋巴细胞亚群。
结果
与健康人相比，OLP患者在中医治疗前CD3、CD4及CD4/CD3比值显著降低（P<0.01），而中医治疗后CD3、CD4及CD4/CD3比值显著升高（P<0.01），且后者恢复至正常水平，8例患者痊愈，14例显著改善，8例改善。
结论
中医治疗对OLP有效。它对患者的免疫平衡具有双向调节作用。
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