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[广东省支气管哮喘的流行病学调查与分析]

[Epidemiological survey and analysis on bronchial asthma in Guangdong Province].

作者信息

Tang T, Ding Y, Zhen J

机构信息

Department of Respiratory Disease, Affiliated Huaqiao Hospital, Medical College of Jinan University, Guangzhou 510630, China.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 2000 Dec;23(12):730-3.

Abstract

OBJECTIVE

To survey asthma prevalence and risk factors of asthma in Guangdong and then to provide a basic consideration for research and preventive and therapeutic poliaes for control of asthma.

METHODS

Using uniform scheme, procedures and questionnaire, performing stratified-cluster-disproportional-random-sampling survey for the population in six areas: Santou, Shenzhen, Zhanjiang, Shaoguan, Fushan and Guangzhou; quantitative sample the prevalence rate quantitated is 1.5% (P = 0.015, q = 0.985), a sampling number stratified = 178 x 0.985/0.015 = 11,689, if the whole province were stratified into six areas, a total of 70,134 persons were supposed to be investigated, in this survey 71,867 subjects were actually examined; all the original data were inputted into soft discs in the same form of data base structure variable definition table, and then were statistically analyzed with spas 8.0 for windows on P III/450 computer, all the prevalence rates were compared by chi 2 test.

RESULTS

In this survey 676 asthmatics were found, the overall prevalence rate was 0.94%, the ratio of male to female was 1.38:1; the rate of adults was 0.99% and that of children was 0.73%, three groups with higher prevalence were children of preschool period (age < 7 years, 1.03%), young period (age 18-25 years, 1.00%) and senile period (age 66-75 years, 2.99%); the rate of city (Fushan, 1.38%) was higher than that of rural area (Zhanjiang, 0.47%); the rate of old district (1.70%) was higher than that of the new district (0.23%) in Guangzhou and the rate of historic city (Fushan, 1.38%) was higher than that of the newly developed city (Shenzhen, 0.64%); risk factors found among 676 asthmatics, persons keeping pets (cat, dog, fowl, bird) in home were reported by 46.0% (311/676), those keeping cat was 43.1% (134/311), particularly those keeping cat and both cat and dog accounted for 61.7% (192/311). Persons often exposed to side-stream smoke were reported by 54.7%. Asthmatics with allergic rhinititis were reported by 38.2%. The attack contributed to change temperature or to inhale cold air was 41.6% respectively.

CONCLUSION

This survey had basically reflected the distribution, Frequency and intensity of asthma, the overall prevalence rate was 0.94% from which it would be estimated that there could be 670,000 asthmatics in Guangdong; the relative data will provide basis for research work concerned and mass prevention and treatment of asthma.

摘要

目的

调查广东地区哮喘患病率及其危险因素,为哮喘防治研究及防治策略提供依据。

方法

采用统一方案、程序和问卷,对汕头、深圳、湛江、韶关、佛山和广州六个地区的人群进行分层整群非比例随机抽样调查;定量抽样患病率为1.5%(P = 0.015,q = 0.985),分层抽样人数 = 178×0.985/0.015 = 11689人,若全省分为六个地区,则应调查70134人,本次调查实际检查71867人;所有原始数据按数据库结构变量定义表的相同形式录入软盘,然后在P III/450计算机上用Windows版spas 8.0进行统计分析,所有患病率用χ²检验进行比较。

结果

本次调查发现哮喘患者676例,总患病率为0.94%,男女比例为1.38∶1;成人患病率为0.99%,儿童患病率为0.73%,患病率较高的三个群体是学龄前儿童(年龄<7岁,1.03%)、青年期(年龄18 - 25岁,1.00%)和老年期(年龄66 - 75岁,2.99%);城市(佛山,1.38%)患病率高于农村(湛江,0.47%);广州老城区(1.70%)患病率高于新城区(0.23%),历史文化名城(佛山,1.38%)患病率高于新兴城市(深圳,0.64%);在676例哮喘患者中发现的危险因素,家中饲养宠物(猫、狗、禽、鸟)的占46.0%(311/676),养猫的占43.1%(134/311),其中养猫且同时养狗的占61.7%(192/311)。经常接触侧流烟雾的占54.7%。患过敏性鼻炎的哮喘患者占38.2%。因气温变化或吸入冷空气诱发发作的分别占41.6%。

结论

本次调查基本反映了哮喘的分布、发病频率和强度,总患病率为0.94%,据此估计广东地区哮喘患者约67万;相关数据将为哮喘防治研究及群防群治工作提供依据。

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