Gong J, Zhang R, Chen H
Department of General Surgery, Jiangsu Cancer Hospital, Nanjing 210009, China.
Zhonghua Zhong Liu Za Zhi. 2000 Jul;22(4):324-6.
To reveal the clinical characteristics, causes of misdiagnosis, treatment and prognosis of thyroid carcinoma in children.
Fourteen patients under 14 years of age with thyroid carcinoma were retrospectively reviewed.
According to UICC's clinical and histopathologic classification (1989), there were 12 cases of papillary carcinomas (83.3%), 2 cases of follicular carcinomas (16.7%). All but one case were in stage I. Cervical lymph node metastasis was found in 12 cases (85.7%). Diagnosis was incorrect in 7 cases. All patients were operated, including unilateral neck dissection in 11 and bilateral neck dissection in 2. One patient received palliative subthyroidectomy and postoperative 131I treatment. In the follow-up period of 2 to 13 years (mean 6 years), no patient died.
Thyroid cancer in children are mostly papillary carcinomas with good prognosis, regardless of high frequency of cervical lymph node metastases. Early cases can be picked up if misdiagnosis be avoided.
揭示儿童甲状腺癌的临床特征、误诊原因、治疗方法及预后。
回顾性分析14例14岁以下甲状腺癌患儿的临床资料。
根据国际抗癌联盟（UICC）1989年的临床和组织病理学分类，乳头状癌12例（83.3%），滤泡状癌2例（16.7%）。除1例患者外，其余均为Ⅰ期。12例（85.7%）发现颈部淋巴结转移。7例诊断错误。所有患者均接受手术治疗，其中11例行单侧颈清扫术，2例行双侧颈清扫术。1例患者接受姑息性甲状腺次全切除术及术后131I治疗。随访2至13年（平均6年），无患者死亡。
儿童甲状腺癌多为乳头状癌，预后良好，尽管颈部淋巴结转移发生率较高。避免误诊可早期发现病例。
