Meren M, Jannus-Pruljan L, Loit H M, Põlluste J, Jönsson E, Kiviloog J, Lundbäck B
Department of Pulmonology, Institute of Experimental and Clinical Medicine, Tallinn, Estonia.
Respir Med. 2001 Dec;95(12):954-64. doi: 10.1053/rmed.2001.1188.
Epidemiological studies indicate a lower prevalence of asthma in Eastern than Western Europe. This study of the prevalence of asthma, chronic bronchitis, and respiratory symptoms was performed in three different regions of Estonia, a state incorporated in the Soviet Union until 1991. A postal questionnaire was sent to a random sample of 24,307 of the population aged 15-64 years. The response rate was 77.6%. The prevalence of physician-diagnosed asthma was 2.0% or considerably lower than in Northern and Western European countries. The prevalence of wheezing last 12 months, 21.7%, recurrent wheeze, 13.3%, and attacks of shortness of breath, 12.5%, were similar or even higher compared with prevalence rates found in the Nordic countries. The prevalence of physician-diagnosed chronic bronchitis was 10.7%, and was higher among women than in men, although the proportion of current smokers among men, 57%, was considerably greater than in women, 28%. A possible explanation to the high prevalence of respiratory symptoms also among non-smoking women may be exposure to environmental tobacco smoke in small, crowded Estonian homes. Diagnostic criteria based on the Soviet-time definitions is discussed as a possible explanation to the low prevalence of physician-diagnosed asthma and high prevalence of chronic bronchitis in Estonia compared with other Northern European countries.
流行病学研究表明,东欧哮喘的患病率低于西欧。本研究针对爱沙尼亚三个不同地区的哮喘、慢性支气管炎及呼吸道症状患病率展开,爱沙尼亚在1991年之前是苏联的加盟共和国。向年龄在15 - 64岁的24307名随机抽取的人群邮寄了调查问卷。回复率为77.6%。医生诊断的哮喘患病率为2.0%,显著低于北欧和西欧国家。过去12个月喘息的患病率为21.7%,复发性喘息为13.3%,气短发作患病率为12.5%,与北欧国家的患病率相似甚至更高。医生诊断的慢性支气管炎患病率为10.7%,女性患病率高于男性,尽管男性中当前吸烟者的比例为57%,远高于女性的28%。非吸烟女性中呼吸道症状患病率较高的一个可能原因可能是爱沙尼亚狭小拥挤的家庭环境中存在环境烟草烟雾。文中讨论了基于苏联时期定义的诊断标准,以此作为爱沙尼亚与其他北欧国家相比医生诊断哮喘患病率低、慢性支气管炎患病率高的一个可能解释。