Vinorelbine-associated myelopathy in a patient who previously received paclitaxel: a case report.
作者信息
Han J Y, Choi B G, Song D H, Ahn J G, Yoon J S, Lee K S
机构信息
Departments of Internal Medicine, College of Medicine, the Catholic University of Korea, Seoul.
出版信息
Med Oncol. 2001;18(1):95-7. doi: 10.1385/MO:18:1:95.
PMID:11778975
Abstract
Vinorelbine seems to cause less neurotoxicity than other vinca alkaloids because of its selective activity on mitotic cells over axonal microtubules. Clinical trials report very mild peripheral neurotoxicity with distal paresthesiae and there are no reports of myelopathy in these series of patients. The authors describe a patient who developed a rare event of myelopathy while on vinorelbine for non-small-cell lung cancer.
摘要
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