Borodiiuk N A, Liampert I M
Biull Eksp Biol Med. 1979 Sep;88(9):319-22.
It was shown in the gel precipitation tests that absorption of human and rabbit IgG or Fc-fragments obtained from human IgG group A streptococcal cultures results in inhibition of the reactions of these preparations with immunoglobulin sera. The reactions of F(ab')2-fragments with the corresponding sera are not inhibited during their absorption by the same cultures. The results obtained support the presence in a number of group A streptococcal cultures of immunoglobulin receptors (Ig-receptors) capable of reacting with Fc-parts of human and rabbit IgG. Pepsin treatment destroys Ig-receptors. These receptors could not be found by the method used in hydrochloric acid extracts prepared from streptococci containing the receptors. The method can be applied for determination of Ig-receptors in streptococcal cultures.
凝胶沉淀试验表明,从人IgG A组链球菌培养物中获得的人及兔IgG或Fc片段的吸收会导致这些制剂与免疫球蛋白血清的反应受到抑制。F(ab')2片段与相应血清的反应在被相同培养物吸收时不会受到抑制。所得结果支持在许多A组链球菌培养物中存在能够与人及兔IgG的Fc部分发生反应的免疫球蛋白受体(Ig受体)。胃蛋白酶处理会破坏Ig受体。在用含有受体的链球菌制备的盐酸提取物中,通过所使用的方法无法找到这些受体。该方法可用于测定链球菌培养物中的Ig受体。