Watanabe H, Onizawa K, Naito S, Taguchi H, Goto N, Nagao T, Matsuo N, Tokimitsu I, Yasukawa T, Tsushima R, Shimasaki H, Itakura H
Biological Science Laboratories, Kao Corporation, 2606, Akabane, Ichikai-machi, Haga-gun, Tochigi 321-3497, Japan.
Ann Nutr Metab. 2001;45(6):259-64. doi: 10.1159/000046736.
The objective of this study was to examine the effect of dietary diacylglycerol (DAG) on the bioavailability of fat-soluble vitamins in comparison with triacylglycerol (TAG).
We conducted a long-term administration test of DAG and TAG in 27 healthy men aged 27-47 years. After measuring baseline values, subjects were randomized into two groups, one group (n = 15) was given DAG and the other (n = 12) was given TAG. Subjects ingested 20 g of DAG or TAG either in mayonnaise or an emulsion drink of their own choice at meals once a day for 12 weeks. At 4, 8 and 12 weeks, fasting blood samples were drawn and serum levels of vitamin A, E, and D were measured.
There were no significant changes in vitamin A levels throughout the study period. Compared to the initial values (using a Student's t test for paired values), significant differences of vitamin E and D were seen at some points during the experiment. According to a two-way repeated measures analysis of variance, however, DAG and TAG (lipid) and time had no effect on fat-soluble vitamin levels.
Our results indicate that DAG does not affect the absorption of the fat-soluble vitamins in diets.
本研究的目的是与三酰甘油（TAG）相比，研究膳食二酰甘油（DAG）对脂溶性维生素生物利用度的影响。
我们对27名年龄在27至47岁的健康男性进行了DAG和TAG的长期给药试验。在测量基线值后，将受试者随机分为两组，一组（n = 15）给予DAG，另一组（n = 12）给予TAG。受试者每天在进餐时选择蛋黄酱或乳液饮料中摄入20克DAG或TAG，持续12周。在第4、8和12周，采集空腹血样并测量血清中维生素A、E和D的水平。
在整个研究期间，维生素A水平没有显著变化。与初始值相比（使用配对值的学生t检验），在实验过程中的某些时间点观察到维生素E和D有显著差异。然而，根据双向重复测量方差分析，DAG和TAG（脂质）以及时间对脂溶性维生素水平没有影响。
我们的结果表明，DAG不影响饮食中脂溶性维生素的吸收。
