Kessler Peter A, Merten Hans A, Neukam Friedrich W, Wiltfang Jörg
Department of Oral and Maxillofacial Surgery, University of Erlangen-Nuremberg, Germany.
Plast Reconstr Surg. 2002 Jan;109(1):171-80. doi: 10.1097/00006534-200201000-00027.
Callus distraction has become an accepted treatment procedure to lengthen hypoplastic mandibles in humans. For this purpose, extraoral and intraoral devices have been applied successfully. The effects of the distraction vector, distractor stability, and rate and frequency of callus distraction on the regenerating tissues have been examined in various studies. In an experimental animal trial on pigs (n = 12), a newly developed microhydraulic osteodistractor was tested. The animals were evenly assigned to two groups to perform a continuous and noncontinuous osteodistraction of the mandible. Initially, the forces necessary to distract the pig mandibles were recorded from a noncontinuous distraction procedure; the results were then used to perform continuous bone distraction. Besides testing the new distractor, the study proved that in continuous osteodistraction, intramembranous bone regeneration occurred, whereas in noncontinuous osteodistraction the bone regeneration process followed a chondroid ossification. In continuous osteodistraction, the bone regeneration proceeded at a higher speed with the lower distraction forces compared with noncontinuous distraction, thereby reducing the consolidation period. Clinical and microscopical results are presented.
骨痂牵张已成为治疗人类发育不全下颌骨延长的一种公认治疗方法。为此，口外和口内装置已成功应用。在各种研究中，已经研究了牵张向量、牵张器稳定性以及骨痂牵张的速率和频率对再生组织的影响。在一项对猪（n = 12）的实验动物试验中，测试了一种新开发的微液压骨牵张器。将动物平均分为两组，对下颌骨进行连续和非连续的骨牵张。最初，通过非连续牵张程序记录牵张猪下颌骨所需的力；然后将结果用于进行连续骨牵张。除了测试新的牵张器外，该研究还证明，在连续骨牵张中，发生膜内骨再生，而在非连续骨牵张中，骨再生过程遵循软骨样骨化。与非连续牵张相比，在连续骨牵张中，较低的牵张力使骨再生速度更快，从而缩短了愈合期。本文展示了临床和显微镜检查结果。
