Pépin G, Vayssette F, Gaillard Y
Laboratoire d'expertise TOXLAB, 7, rue Jacques Cartier, F75018 Paris.
Ann Pharm Fr. 2001 Sep;59(5):345-9.
The French National Laboratory of the International Olympic Committee (IOC) has detected norandrosterone (NA) and noretiocholanolone (NE) in urine samples from several sportsmen. These two substances are known to be urinary metabolites after nandrolone intake. In such cases, the NA level is always higher than the Ne level. However, in the urine samples of sportsmen tested positive, the NE concentrations were systematically higher than the NA levels. We therefore searched for other steroid precursors (commercially available capsules or tablets of dehydroepiandrosterone, 4-androstenediol, 5-androstenediol, 4-androstenedione, 19-norandrostenediol and 19-norandrostenedione, also illegally used in France) which could lead to an excretion of NA and NE and to an inverted ratio of these metabolites.
法国国家奥委会实验室在多名运动员的尿液样本中检测出了去甲雄酮（NA）和去甲表雄酮（NE）。已知这两种物质是摄入诺龙后的尿液代谢产物。在这种情况下，NA水平总是高于NE水平。然而，在检测呈阳性的运动员尿液样本中，NE浓度却系统性地高于NA水平。因此，我们寻找了其他可能导致NA和NE排泄以及这些代谢产物比例倒置的类固醇前体（在法国也被非法使用的脱氢表雄酮、4-雄烯二醇、5-雄烯二醇、4-雄烯二酮、19-去甲雄烯二醇和19-去甲雄烯二酮的市售胶囊或片剂）。
