Eadie M J
University of Medicine, University of Queensland, Brisbane, Australia.
J Clin Neurosci. 2001 Nov;8(6):514-9. doi: 10.1054/jocn.2001.0935.
The Australian Alfred Walter Campbell (1868-1937) is remembered as one of the two chief pioneers of the study of the cytoarchitectonics of the primate cerebral cortex. He had worked in Britain carrying out neuroanatomical and neuropathological research for almost two decades before his famous monograph on Histological Studies on the Localisation of Cerebral Function appeared in 1905. In that year he returned to his native Australia and practiced for over 30 years in Sydney as a neurologist rather than a neuropathologist, publishing mainly clinical material though he was involved in the investigation of the epidemic of Australian X disease, a viral encephalitis. His abrupt change in both the nature and the location of his career at a time when he was well established in Britain appears to have been a consequence of his marriage and the need to provide for a family. His simultaneous apparent abandonment of research seems not to have really been the case. As judged from the contents of a paper presented to a local medical congress in Sydney in 1911, it appears that, in Australia, Campbell did carry out a major comparative anatomical and histological investigation of the possibility of localization of function in the cerebellar cortex. He never published this work in detail. His investigation let him to conclude that no such localization of function existed, a view contrary to the then topical interpretation of Bolk (1906), but one in accordance with Gordon Holmes' views a decade later. Campbell's circumstances in Sydney, his extremely reticent nature and the essentially negative outcome of his investigation probably explain his failure to make his study more widely known.
澳大利亚人阿尔弗雷德·沃尔特·坎贝尔(1868 - 1937)被誉为灵长类动物大脑皮质细胞构筑学研究的两位主要先驱之一。在其1905年发表著名的关于《大脑功能定位的组织学研究》专著之前,他已在英国从事神经解剖学和神经病理学研究近二十年。同年,他回到祖国澳大利亚,在悉尼作为神经学家而非神经病理学家执业了30多年,主要发表临床资料,尽管他参与了澳大利亚X病(一种病毒性脑炎)的流行病学调查。在他于英国已站稳脚跟之时,其职业性质和地点的突然转变似乎是他结婚以及需要养家的结果。他同时看似放弃研究的情况似乎并非如此。从1911年提交给悉尼当地医学大会的一篇论文内容判断,在澳大利亚,坎贝尔确实对小脑皮质功能定位的可能性进行了一项重大的比较解剖学和组织学研究。他从未详细发表这项研究成果。他的研究使他得出结论,不存在这样的功能定位,这一观点与当时博尔克(1906年)的热门解释相反,但与十年后戈登·霍姆斯的观点一致。坎贝尔在悉尼的情况、他极度沉默寡言的性格以及他研究的基本负面结果,可能解释了他未能让自己的研究更广为人知的原因。