Guggenheimer J, Fischer W G, Pechersky J L
Radiology. 1975 Nov;117(2):405-6. doi: 10.1148/117.2.405.
Therapeutic irradiation of the head and neck of children up to the age of 16 years can cause malformation and developmental arrest of the permanent teeth. Dental anomalies occurring after irradiation of the palatal tumor in an 8-year-old are described and compared with a normal 8-year-old's developmental sequence to demonstrate that the immature, noncalcified dental structures are most susceptible to radiation injury. The stage of dental development at the time of therapy may be precisely determined by a routine oral radiographic survey, which provides a reliable estimate of the deformation that may be anticipated following radiotherapy.
对16岁以下儿童的头颈部进行治疗性照射会导致恒牙畸形和发育停滞。本文描述了一名8岁儿童腭部肿瘤放疗后出现的牙齿异常情况，并与一名正常8岁儿童的发育序列进行比较，以证明未成熟、未钙化的牙齿结构最易受到辐射损伤。治疗时牙齿的发育阶段可通过常规口腔X光检查精确确定，该检查能可靠估计放疗后可能出现的牙齿变形情况。
