疗养院中潜在不适当药物的使用。
Use of potentially inappropriate drugs in nursing homes.
作者信息
Dhall Jyotsna, Larrat E Paul, Lapane Kate L
机构信息
Department of Applied Pharmaceutical Sciences, University of Rhode Island, Kingston, USA.
出版信息
Pharmacotherapy. 2002 Jan;22(1):88-96. doi: 10.1592/phco.22.1.88.33503.
STUDY OBJECTIVES
To examine patterns and determine predictors of inappropriate drug use in nursing homes.
DESIGN
Retrospective study.
SETTING
One thousand four hundred ninety-two nursing homes in five states.
PATIENTS
A total of 44,562 residents admitted to nursing homes over 1 year.
METHODS
Frequency of discontinuation and initiation of potentially inappropriate drugs over the first 90 days after admission to a nursing home was calculated. Data were collected using the minimum data set.
RESULTS
On admission, 33% of residents were receiving at least one potentially inappropriate drug. After 90 days, the drug was discontinued in 16% of these residents. Of those not receiving a potentially inappropriate drug on admission, one was begun in 18%. Demographic factors and number of drugs taken by patients were associated with the use of potentially inappropriate drugs. CONCLUSIONS; Use of potentially inappropriate drugs was prevalent on admission and at 90 days after admission. Discontinuation was highest among patients with conditions for which potentially safer therapeutic alternatives existed.
研究目的
研究养老院中不适当用药的模式并确定其预测因素。
设计
回顾性研究。
地点
五个州的1492家养老院。
患者
一年内共44562名入住养老院的居民。
方法
计算入住养老院后前90天内停用和启用潜在不适当药物的频率。使用最小数据集收集数据。
结果
入院时，33%的居民至少正在服用一种潜在不适当药物。90天后，这些居民中有16%停用了该药物。入院时未服用潜在不适当药物的居民中，有18%开始服用了一种。人口统计学因素和患者服用的药物数量与潜在不适当药物的使用有关。结论：潜在不适当药物的使用在入院时和入院后90天很普遍。在存在潜在更安全治疗替代方案的疾病患者中停药率最高。
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