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妊娠糖尿病:与门诊管理相比住院治疗的疗效及成本——一项前瞻性对照研究

Diabetes in pregnancy: efficacy and cost of hospitalization as compared with ambulatory management--a prospective controlled study.

作者信息

Nachum Z, Ben-Shlomo I, Weiner E, Ben-Ami M, Shalev E

机构信息

Department of Obstetrics and Gynecology, HaEmek Medical Center, Afula, Israel.

出版信息

Isr Med Assoc J. 2001 Dec;3(12):915-9.

Abstract

BACKGROUND

Pregnant diabetic women are often subjected to frequent and prolonged hospitalizations to assure tight glycemic control, but in recent years attempts have been made at ambulatory control. The financial and social advantages of ambulatory management are obvious, but no report to date has prospectively compared its efficacy with that of hospitalization.

OBJECTIVES

To evaluate the efficacy and cost of ambulatory care as compared to repeated hospitalizations for management of diabetes in pregnancy.

METHODS

We conducted an 8 year prospective controlled study that included 681 diabetic women, experiencing 801 singleton pregnancies, with commencement of therapy prior to 34 gestational weeks. During 1986-1989, 394 pregnancies (60 pregestational diabetes mellitus and 334 gestational diabetes mellitus) were managed by hospitalization, and for the period 1990-1993, 407 pregnancies (61 PGDM and 346 GDM) were managed ambulatorily. Glycemic control, maternal complications, perinatal mortality, neonatal morbidity and hospital cost were analyzed.

RESULTS

There was no difference in metabolic control and pregnancy outcome in women with PGDM between the hospitalized and the ambulatory groups. Patients with GDM who were managed ambulatorily had significantly lower mean capillary glucose levels, later delivery and higher gestational age at induction of labor as compared to their hospitalized counterparts. In this group there were also lower rates of neonatal hyperbilirubinemia, phototherapy and intensive care unit admissions and stay. The saved hospital cost (in Israeli prices) in the ambulatory group was $6,000 and $15,000 per GDM and PGDM pregnancy, respectively.

CONCLUSIONS

Ambulatory care is as effective as hospitalization among PGDM patients and more effective among GDM patients with regard to glycemic control and neonatal morbidity. This is not only more convenient for the pregnant diabetic patient, but significantly reduces treatment costs.

摘要

背景

妊娠糖尿病妇女常因确保严格的血糖控制而频繁且长期住院,但近年来已尝试进行门诊管理。门诊管理在经济和社会方面的优势显而易见,但迄今为止尚无前瞻性研究比较其与住院治疗的疗效。

目的

评估门诊护理与多次住院治疗妊娠糖尿病的疗效及成本。

方法

我们进行了一项为期8年的前瞻性对照研究,纳入681例糖尿病妇女,她们共经历801次单胎妊娠,均在妊娠34周前开始治疗。1986 - 1989年期间,394例妊娠(60例孕前糖尿病和334例妊娠期糖尿病)采用住院治疗,1990 - 1993年期间,407例妊娠(61例孕前糖尿病和346例妊娠期糖尿病)采用门诊治疗。分析了血糖控制情况、母体并发症、围产期死亡率、新生儿发病率及住院费用。

结果

孕前糖尿病妇女的住院组和门诊组在代谢控制和妊娠结局方面无差异。与住院治疗的妊娠期糖尿病患者相比,门诊治疗的患者平均毛细血管血糖水平显著更低,分娩时间更晚,引产时孕周更大。该组新生儿高胆红素血症、光疗及入住重症监护病房的比例和时间也更低。门诊组每例妊娠期糖尿病和孕前糖尿病妊娠节省的住院费用(以以色列货币计)分别为6000美元和15000美元。

结论

在血糖控制和新生儿发病率方面,门诊护理在孕前糖尿病患者中与住院治疗效果相同,在妊娠期糖尿病患者中更有效。这不仅对妊娠糖尿病患者更方便,还显著降低了治疗成本。

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