Heldt T, Shim E B, Kamm R D, Mark R G
Massachusetts Institute of Technology, Cambridge, MA, USA.
Comput Cardiol. 1999;26:213-6.
The work presented in this paper is part of an ongoing effort to use mathematical models to investigate the effects of microgravity on the cardiovascular system. In particular, a thirteen compartment lumped parameter representation of the cardiovascular system is used to simulate some of the current hypotheses concerning the mechanism of post-flight orthostatic intolerance. Simulations are compared to astronaut stand test data pre - and post-flight in an effort to quantitatively evaluate alternative hypotheses.
本文所展示的工作是利用数学模型研究微重力对心血管系统影响的持续努力的一部分。具体而言,心血管系统的十三房室集总参数表示法被用于模拟一些当前关于飞行后体位性不耐受机制的假设。将模拟结果与宇航员飞行前和飞行后的立位试验数据进行比较,以定量评估各种假设。