Danchev P, Georgiev S
Vet Med Nauki. 1975;12(7):28-33.
Immunoelectrophoretic studies were carried out with the sera obtained from 10 chickens affected with acute Marek's disease. The diagnosis was confirmed clinically, morphologically, and via the embryonic test of von Bulow. The blood sera of ten normal hens served as controls. Results showed that in the sera of the diseased chickens there were changes in the protein spectrum, whereas the alfa and gamma-globulin fractions were divided into three subfractions. The exhaustion of the diseased sera with hyperimmune sera against sera of normal chickens revealed characteristic alfa2-globulins. The results obtained were confirmed with the active anaphylaxis in guinea-pigs.
对10只患有急性马立克氏病的鸡的血清进行了免疫电泳研究。临床、形态学以及通过冯·布洛胚胎试验确诊了该病。10只正常母鸡的血清用作对照。结果显示，患病鸡的血清中蛋白质谱有变化，而α和γ球蛋白组分被分为三个亚组分。用抗正常鸡血清的超免疫血清耗尽患病血清后，发现了特征性的α2球蛋白。在豚鼠身上进行的主动过敏反应证实了所获得的结果。
