Ragunath K, Williams J G
Department of Gastroenterology, Neath General Hospital, Neath, South Wales, UK.
Postgrad Med J. 2002 Jan;78(915):34-6. doi: 10.1136/pmj.78.915.34.
Although several modalities are available to investigate oesophageal motility disorders, manometry is the gold standard. The procedure is increasingly available in district general hospitals but the clinical utility of this investigation in this setting remains unclear. The aim in this study was to evaluate the use and outcome of oesophageal manometry in a district general hospital. Data on 100 consecutive oesophageal manometry procedures were analysed, taking into account the referral pattern, indications, and results. The indications were gastro-oesophageal reflux disease (preoperative assessment before fundoplication) (58), dysphagia (28), chest pain (12), and epigastric pain (2). Diagnoses were made using predefined standard criteria and were as follows: normal (41), non-specific motility disorder (NSMD) (38), achalasia (15), diffuse oesophageal spasm (4), and scleroderma (2). Of the 58 patients who had undergone manometry as a preoperative assessment of oesophageal motility, 27 (47%) were abnormal. Twenty five (43%) had NSMD and two (3%) had achalasia. Forty eight of these preoperative cases were combined with 24 hour pH recording, which confirmed acid reflux in 35 (73%). The experience reported here reflects the published evidence that the use of manometry is changing. It is now more commonly used for assessment before antireflux surgery and for dysphagia, and the use in the assessment of chest pain is declining. The findings confirm the importance of eliminating achalasia before inappropriate antireflux surgery.
尽管有多种方法可用于研究食管动力障碍,但食管测压是金标准。该检查在地区综合医院越来越普及,但在这种情况下该检查的临床实用性仍不明确。本研究的目的是评估地区综合医院食管测压的应用情况及结果。分析了连续100例食管测压检查的数据,同时考虑了转诊模式、检查指征和结果。检查指征包括胃食管反流病(胃底折叠术前评估)(58例)、吞咽困难(28例)、胸痛(12例)和上腹痛(2例)。诊断采用预定义的标准,结果如下:正常(41例)、非特异性动力障碍(NSMD)(38例)、贲门失弛缓症(15例)、弥漫性食管痉挛(4例)和硬皮病(2例)。在58例作为食管动力术前评估而接受测压的患者中,27例(47%)异常。25例(43%)为NSMD,2例(3%)为贲门失弛缓症。其中48例术前病例同时进行了24小时pH监测,35例(73%)证实有酸反流。此处报告的经验反映了已发表的证据,即食管测压的应用正在发生变化。现在它更常用于抗反流手术前的评估和吞咽困难的评估,而用于胸痛评估的情况正在减少。这些发现证实了在进行不适当的抗反流手术前排除贲门失弛缓症的重要性。