Miyake K
Department of Clinical Pathology, Juntendo University School of Medicine.
Rinsho Byori. 2001 Nov;Suppl 116:90-9.
Although "lipase" contains various lypolytic enzymes, the main object of lipase measurement is pancreatic lipase. Recent advances in pancreatic lipase research clarified its unique structure, and two novel pancreatic proteins, PLRL 1 and 2, were added to the pancreatic lipase gene family. In pancreatic lipase measurement, several new specific, sensitive, and reproducible assay methods were developed, and they have been widely adapted as routine tests. With these modern assays, pancreatic lipase has a good diagnostic utility for pancreatic disease.
尽管“脂肪酶”包含多种脂解酶,但脂肪酶测定的主要对象是胰腺脂肪酶。胰腺脂肪酶研究的最新进展阐明了其独特结构,并且两种新的胰腺蛋白PLRL 1和2被添加到胰腺脂肪酶基因家族中。在胰腺脂肪酶测定方面,开发了几种新的特异、灵敏且可重复的检测方法,它们已被广泛用作常规检测。借助这些现代检测方法,胰腺脂肪酶对胰腺疾病具有良好的诊断效用。