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[胰脂肪酶]

[Pancreatic lipase].

作者信息

Miyake K

机构信息

Department of Clinical Pathology, Juntendo University School of Medicine.

出版信息

Rinsho Byori. 2001 Nov;Suppl 116:90-9.

PMID:11797385
Abstract

Although "lipase" contains various lypolytic enzymes, the main object of lipase measurement is pancreatic lipase. Recent advances in pancreatic lipase research clarified its unique structure, and two novel pancreatic proteins, PLRL 1 and 2, were added to the pancreatic lipase gene family. In pancreatic lipase measurement, several new specific, sensitive, and reproducible assay methods were developed, and they have been widely adapted as routine tests. With these modern assays, pancreatic lipase has a good diagnostic utility for pancreatic disease.

摘要

尽管“脂肪酶”包含多种脂解酶,但脂肪酶测定的主要对象是胰腺脂肪酶。胰腺脂肪酶研究的最新进展阐明了其独特结构,并且两种新的胰腺蛋白PLRL 1和2被添加到胰腺脂肪酶基因家族中。在胰腺脂肪酶测定方面,开发了几种新的特异、灵敏且可重复的检测方法,它们已被广泛用作常规检测。借助这些现代检测方法,胰腺脂肪酶对胰腺疾病具有良好的诊断效用。

相似文献

1
[Pancreatic lipase].[胰脂肪酶]
Rinsho Byori. 2001 Nov;Suppl 116:90-9.
2
Diagnostic use of pancreatic lipase determination by radial enzyme diffusion, and design of a routine pancreatic profile.通过放射状酶扩散法测定胰脂肪酶用于诊断,并设计常规胰腺检查项目。
Clin Chem. 1976 May;22(5):638-42.
3
[A study of the specificity of amylases. Measurement of pancreatic isoamylases (author's transl)].淀粉酶特异性的研究。胰腺同工淀粉酶的测定(作者译)
Nouv Presse Med. 1980 Nov 1;9(41):3079-81.
4
Serum levels of pancreatic enzymes and their clinical significance.
Clin Gastroenterol. 1984 Sep;13(3):739-61.
5
Serum amylase and lipase. Newer perspectives.血清淀粉酶和脂肪酶。新视角。
JAMA. 1967 Jan 9;199(2):98-102.
6
[Methods and problems in the determination of pancreatic lipase activity in the serum].[血清中胰脂肪酶活性测定的方法与问题]
Dtsch Gesundheitsw. 1973 Jan 1;28(1):33-8.
7
Advances in the enzyme diagnosis of pancreatic diseases.胰腺疾病酶诊断的进展。
Clin Biochem. 1990 Oct;23(5):383-94. doi: 10.1016/0009-9120(90)90102-z.
8
Enzyme immunoassay for pancreatic lipase: comparison with turbidimetric method in pancreatic diseases.
Clin Biochem. 1985 Aug;18(4):230-2. doi: 10.1016/s0009-9120(85)80045-x.
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[Benign pancreatic hyperenzynemia or Gullo's syndrome].[良性胰腺高酶血症或古洛综合征]
Recenti Prog Med. 2008 Jul-Aug;99(7-8):367-71.
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Clinical evaluation of a new rapid assay for serum lipase determination.
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