Chen M, Gao W, Zhu G, Huo Y
First Teaching Hospital of Beijing Medical University, Beijing 100034.
Zhonghua Nei Ke Za Zhi. 1999 Jan;38(1):27-9.
To study the clinical and angiographical characteristics of coronary heart disease (CHD) in CHD patients with non-insulin-dependent diabetes mellitus (NIDDM).
The study was carried out by case control analysis of the clinical manifestations and the data from cine selective coronary angiography.
CHD patients with NIDDM tended to have multiple cardiovascular risk factors. It is likely that NIDDM contributed more to dyslipidemia in the female than in the male. Unstable angina pectoris was found more frequently in CHD patients with NIDDM than in those without. The female CHD patients with NIDDM were more frequently afflicted with myocardial infarction. Moreover, CHD patients with NIDDM had much greater extent of coronary vessel involvement and more diffuse vascular lesion.
The clinical and angiographical findings are quite different in CHD patients with and without NIDDM. The lesions in the coronary arteries tend to be more severe and diffuse in patients with NIDDM.
研究非胰岛素依赖型糖尿病(NIDDM)合并冠心病(CHD)患者的临床及血管造影特征。
通过对临床表现及选择性冠状动脉造影数据进行病例对照分析开展本研究。
NIDDM合并CHD患者往往存在多种心血管危险因素。NIDDM对女性血脂异常的影响可能比男性更大。NIDDM合并CHD患者中不稳定型心绞痛的发生率高于无NIDDM的CHD患者。NIDDM合并CHD的女性患者更易发生心肌梗死。此外,NIDDM合并CHD患者的冠状动脉受累范围更广,血管病变更弥漫。
有或无NIDDM的CHD患者的临床及血管造影表现有很大差异。NIDDM患者的冠状动脉病变往往更严重、更弥漫。