[Influence of whole-body irradiation with 60Co on poly I:C induced interferon in mice (author's transl)].

After whole-body irradiation with 200, 900 und 1500 R on mice Poly I:C induced serum interferon was decreased. 24 and 48 hours p.r. the interferon-synthesis in the three irradiated groups was considerably reduced. Increasing interferon-titer-yet lower than those of not irradiated controls - were found after Poly I:C application 3, 4 and 5 days p.r. in the groups irradiated with 200 and 900 R. In these two groups a relationship between irradiation-dose and interferon-synthesis was recognized.