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Interferon production by and radioprotective effect of poly I : C and tilorone in mice exposed to helium alpha irradiation.

作者信息

Tálas M, Fedorenko B, Bátkai L, Stöger I

出版信息

Acta Microbiol Hung. 1985;32(3):225-31.

PMID:2417438
Abstract

Serum interferon production induced by poly I : C and tilorone and their radioprotective effect in mice exposed to He-alpha particles was studied. The results were compared to those observed after exposure of mice to acute 60Co-gamma irradiation. Interferon production induced by poly I : C was depressed by He-alpha irradiation less than that induced by tilorone. Treatment of mice with poly I : C or tilorone before He-alpha irradiation had no effect on the mortality of animals in contrast to the radioprotective activity of these compounds against 60Co-gamma irradiation.

摘要

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Interferon production by and radioprotective effect of poly I : C and tilorone in mice exposed to helium alpha irradiation.
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