Preston R E, Johnsson L G, Hill J H, Schacht J
Acta Otolaryngol. 1975 Sep-Oct;80(3-4):269-75. doi: 10.3109/00016487509121327.
45CaCl2 was injected into gerbils in single or multiple doses, and the resulting radioactivity in serum, otoconial CaCO3, bone samples, and selected labyrinthine epithelium was determined by liquid scintillation spectrometry. Incorporation into both utricular and saccular otoconia occurred at the rate of 0.06-0.07 nmole Ca++ per day, corresponding to a fractional rate of uptake of 0.1%. The retention of radioactivity had a half-life of approximately 11 days. The rate of incorporation of calcium for the middle ear ossicles was 5-7 times that for otoconia and was similar to that for otic capsule and skeletal bone. The level of 45Ca++ was higher in the pigmented regions of the utricular membranous wall than in the non-pigmented areas of the utricular and ampullary wall and in the stria vascularis.
将45CaCl2以单剂量或多剂量注射到沙鼠体内，然后通过液体闪烁光谱法测定血清、耳石碳酸钙、骨样本以及选定的迷路上皮中的放射性。钙进入椭圆囊和球囊耳石的速率为每天0.06 - 0.07纳摩尔Ca++，相当于摄取分数率为0.1%。放射性的保留半衰期约为11天。中耳听小骨的钙掺入速率是耳石的5 - 7倍，与耳囊和骨骼的掺入速率相似。椭圆囊膜壁色素沉着区域的45Ca++水平高于椭圆囊和壶腹壁以及血管纹的非色素沉着区域。
