Mechigian I, Preston R E, Johnsson L G, Schacht J
Acta Otolaryngol. 1979;88(1-2):56-60. doi: 10.3109/00016487909137140.
The influence of neomycin and streptomycin on the calcium metabolism of the otolithic membranes was investigated in the guinea pig. After chronic treatment with either drug, animals were injected intraperitoneally with radioactive calcium. Retention of calcium in the serum was unaffected by drug treatment, as was the incorporation of radioactivity into bone (femur and otic capsule). Both drugs inhibited the calcium uptake into saccular and utricular otolithic membranes by 30 to 40%.
在豚鼠身上研究了新霉素和链霉素对耳石膜钙代谢的影响。用这两种药物中的任何一种进行长期治疗后，给动物腹腔注射放射性钙。药物治疗对血清中钙的保留没有影响，对放射性物质掺入骨骼（股骨和听囊）也没有影响。两种药物都使球囊和椭圆囊耳石膜对钙的摄取抑制了30%至40%。
