Henriksen O, Alsner T
Acta Physiol Scand. 1975 Sep;95(1):83-8. doi: 10.1111/j.1748-1716.1975.tb10028.x.
The influence of spinal sympathetic blockade upon local regulation of blood flow in subcutaneous adipose tissue was investigated in six subjects. The effect of changes in orthostatic pressure on blood flow in subcutaneous tissue in the crus and distal forearm was measured before and after sympathetic blockade obtained by epidural anesthesia in 4 subjects and by a bilateral sympathectomy in 2 patients suffering from manual hyperhidrosis. Blood flow in subcutaneous tissue measured by 133Xe washout technique decreased by about 40 per cent when the limb was lowered, and remained constant during 30 cm elevation. This was found both before and after the blockade, though in one of the patients, the orthostatic decrease in blood flow was less pronounced 24 h after sympathectomy. Hence central sympathetic reflexes do not alter local orthostatic changes of blood flow in subcutaneous tissue. These changes therefore are most likely due to local mechanisms.
在六名受试者中研究了脊髓交感神经阻滞对皮下脂肪组织局部血流调节的影响。在4名受试者中通过硬膜外麻醉以及在2名患有手部多汗症的患者中通过双侧交感神经切除术获得交感神经阻滞后，测量了4名受试者在立位压力变化对小腿和前臂远端皮下组织血流的影响。当肢体下垂时，用133Xe洗脱技术测量的皮下组织血流减少约40%，在抬高30厘米期间保持恒定。在阻滞前后均发现了这一情况，尽管在其中一名患者中，交感神经切除术后24小时，立位血流减少不太明显。因此，中枢交感神经反射不会改变皮下组织局部立位血流变化。因此，这些变化很可能是由于局部机制引起的。
