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Glial processes are glued to synapses via Ca(2+)-permeable glutamate receptors.

作者信息

Watanabe Masahiko

机构信息

Dept of Anatomy, Hokkaido University School of Medicine, 060-8638, Sapporo, Japan.

出版信息

Trends Neurosci. 2002 Jan;25(1):5-6. doi: 10.1016/s0166-2236(00)01993-7.

DOI:10.1016/s0166-2236(00)01993-7
PMID:11801322
Abstract

Bergmann glia in the cerebellum elaborately ensheathe Purkinje cell dendrites and synapses, and express high levels of Ca(2+)-permeable glutamate receptors (GluRs). Suppression of the Ca(2+) permeability by virus-mediated GluR2 transfer has revealed that GluR-mediated Ca(2+) signaling is essential to maintain both structural and functional connections between the glial cell and the glutamatergic synapses.

摘要

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