Govindaraj S, Cohen M, Genden E M, Costantino P D, Urken M L
Department of Otolaryngology, Mount Sinai Medical Center, New York, NY 10029, USA.
Laryngoscope. 2001 Nov;111(11 Pt 1):1993-8. doi: 10.1097/00005537-200111000-00024.
At the conclusion of this presentation, the participant should be able to discuss the indications and advantages of using acellular dermis in the prevention of post-parotidectomy gustatory sweating (Frey's Syndrome).
Gustatory sweating is a common postoperative problem and a challenge to treat. The purpose of this study was to evaluate the role of acellular dermis in preventing post-parotidectomy gustatory sweating.
Sixty-four patients were randomly assigned to two groups. Group I consisted of 32 patients who underwent a superficial lobe parotidectomy. Group II consisted of 32 patients who underwent a superficial lobe parotidectomy and underwent intraoperative placement of acellular dermis within the parotid bed, between the skin flap and the remaining parotid tissue. The implanted volume of acellular dermis was determined by the amount required to aesthetically restore lateral facial contour. All 64 patients were evaluated for gustatory sweating by identical phone and mail questionnaires. Thirty randomly chosen patients (group I = 15, group II = 15) were evaluated using a modified Minor's Starch-Iodine Test (MSIT). In all 30 patients, the MSIT was administered to both sides of the face.
The responses to questionnaires (N = 64) demonstrated the subjective presence of gustatory sweating in 3 of 32 patients (9.3%) in group I, whereas group II demonstrated a subjective incidence in 1 of 32 patients (3.1%). The objective incidence determined by those who underwent the MSIT (n = 30) revealed a 40% (6) and 0% incidence of Frey's Syndrome in groups I and II, respectively. The complication rate in group I was 9% (3 seromas) and in group II it was 25% (7 seromas and 1 wound infection).
Acellular dermis appears to be an effective method for preventing post-parotidectomy gustatory sweating, despite its higher complication rate.
在本讲座结束时,参与者应能够讨论使用脱细胞真皮预防腮腺切除术后味觉性出汗(弗雷综合征)的适应症和优势。
味觉性出汗是一种常见的术后问题,也是治疗上的一项挑战。本研究的目的是评估脱细胞真皮在预防腮腺切除术后味觉性出汗中的作用。
64例患者被随机分为两组。第一组由32例行浅叶腮腺切除术的患者组成。第二组由32例行浅叶腮腺切除术且术中在腮腺床内、皮瓣与剩余腮腺组织之间植入脱细胞真皮的患者组成。脱细胞真皮的植入量根据美学修复面部外侧轮廓所需的量来确定。所有64例患者均通过相同的电话和邮件问卷对味觉性出汗进行评估。随机选取30例患者(第一组15例,第二组15例)使用改良的米诺淀粉碘试验(MSIT)进行评估。在所有30例患者中,对双侧面部均进行了MSIT检查。
问卷回复(N = 64)显示,第一组32例患者中有3例(9.3%)主观存在味觉性出汗,而第二组32例患者中有1例(3.1%)主观存在味觉性出汗。接受MSIT检查的患者(n = 30)确定的客观发生率显示,第一组和第二组弗雷综合征的发生率分别为40%(6例)和0%。第一组的并发症发生率为9%(3例血清肿),第二组为25%(7例血清肿和1例伤口感染)。
脱细胞真皮似乎是预防腮腺切除术后味觉性出汗的一种有效方法,尽管其并发症发生率较高。