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在腮腺全切除术后使用人脱细胞真皮基质预防耳下凹陷畸形和弗雷综合征。

The use of human acellular dermal matrix in the prevention of infra-auricular depressed deformities and Frey's syndrome following total parotidectomy.

机构信息

Department of Oral & Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, China.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Aug;114(2):e9-13. doi: 10.1016/j.oooo.2011.08.012. Epub 2012 Feb 25.

Abstract

BACKGROUND

The aim of the study was to explore whether human acellular dermal matrix (ADM) implantation could prevent infra-auricular depressed deformities and Frey's syndrome following total parotidectomy.

METHODS

We analyzed 41 cases of total parotidectomy (control group) and 29 cases of simultaneous ADM implantation following total parotidectomy (ADM group) for infra-auricular depressed deformities and the presence of gustatory flushing or sweating. The follow-up periods ranged from 6 months to 7 years.

RESULTS

Facial contours and bilateral symmetry improved after surgery in the ADM group. In the control group, an infra-auricular depressed deformity was evident in all 41 cases. Frey's syndrome was recorded in 1 patient (3.4%) from the ADM group and 14 patients (34.1%) from the control group. No cases of immune rejection, infection, hematoma, or salivary fistula were observed in either group.

CONCLUSIONS

The use of ADM could reduce postoperative facial contour deformities and Frey's syndrome following total parotidectomy.

摘要

背景

本研究旨在探讨人脱细胞真皮基质(ADM)植入是否能预防腮腺切除术后耳下凹陷畸形和 Frey 综合征。

方法

我们分析了 41 例腮腺切除术(对照组)和 29 例腮腺切除术后同时 ADM 植入(ADM 组)患者耳下凹陷畸形和味觉潮红或出汗的情况。随访时间为 6 个月至 7 年。

结果

ADM 组术后面部轮廓和双侧对称性改善。对照组 41 例均出现耳下凹陷畸形。ADM 组有 1 例(3.4%)患者出现 Frey 综合征,对照组有 14 例(34.1%)患者出现 Frey 综合征。两组均未发生免疫排斥、感染、血肿或涎漏。

结论

使用 ADM 可减少腮腺切除术后的面部轮廓畸形和 Frey 综合征。

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