Board J A, Bhatnagar A S
Am J Obstet Gynecol. 1975 Sep 1;123(1):41-5. doi: 10.1016/0002-9378(75)90942-4.
Some patients with galactorrhea will have normal serum prolactin levels but many will have elevated serum prolactin levels. The galactorrhea may be due to drug ingestion, nipple afferent nerve stimulation, nonneoplastic disease or injury, and intracranial tumors. Serum prolactin levels were measured by radioimmunoassay in 17 women with galactorrhea. Levels 5 and 6 times normal values were found in two women who had proved pituitary adenomas. The latter conditions must be strongly considered and functional tests may help in diagnosis prior to enlargement of a prolactin-secreting tumor to the size where changes in the sella are seen on x-ray or visual field changes occur. If galactorrhea persists when no evidence of tumor can be found, the patient must be periodically re-evaluated, as the tumor may have been too small for detection at the time of the previous examination.
一些溢乳患者的血清催乳素水平正常，但许多患者的血清催乳素水平会升高。溢乳可能是由于药物摄入、乳头传入神经刺激、非肿瘤性疾病或损伤以及颅内肿瘤引起的。对17名溢乳女性进行了放射免疫测定血清催乳素水平。在两名已证实患有垂体腺瘤的女性中发现水平为正常值5倍和6倍。必须高度考虑后一种情况，功能测试可能有助于在分泌催乳素的肿瘤增大到在x光片上可见蝶鞍变化或出现视野变化之前进行诊断。如果在找不到肿瘤证据时溢乳持续存在，患者必须定期重新评估，因为肿瘤可能在前一次检查时太小而无法检测到。
