极高产次：它是一个产科危险因素吗？
Extreme grandmultiparity: is it an obstetric risk factor?
作者信息
Kumari Aruna S, Badrinath Padmanabhan
机构信息
Department of Obstetrics and Gynaecology, Al-Mafraq Hospital, P.O. Box 2951, Abu Dhabi, United Arab Emirates.
出版信息
Eur J Obstet Gynecol Reprod Biol. 2002 Feb 10;101(1):22-5. doi: 10.1016/s0301-2115(01)00498-5.
OBJECTIVE
To examine the perinatal outcome in women of extreme grandmultiparity (EGMP) in a setting with good socio-economic conditions and modern perinatal care.
METHODS
About 1015 pregnant women with a parity of 10 and above who delivered at Al-Mafraq hospital, Abu Dhabi between 1992 and 1998 were compared with 2044 women of parity <5 and 1662 with parity of 5-9.
RESULTS
Pregnant women with parity of 10 and above had an increased incidence of gestational diabetes (P<0.001) and macrosomia (P<0.001) and a reduced incidence of preterm delivery (P<0.0001) and induction of labor (P<0.0001). There were no significant differences between the groups regarding, antepartum hemorrhage, cesarean section rate and neonatal outcomes.
CONCLUSION
Extreme grandmultiparity does not appear to be an independent risk factor for adverse perinatal outcome in the setting of good perinatal care.
目的
在社会经济条件良好且具备现代围产期护理的环境中，研究极高产次（EGMP）女性的围产期结局。
方法
将1992年至1998年期间在阿布扎比的Al-Mafraq医院分娩的约1015名产次为10次及以上的孕妇，与2044名产次<5次的女性以及1662名产次为5 - 9次的女性进行比较。
结果
产次为10次及以上的孕妇妊娠期糖尿病发病率增加（P<0.001）、巨大儿发病率增加（P<0.001），早产发病率降低（P<0.0001）以及引产率降低（P<0.0001）。在产前出血、剖宫产率和新生儿结局方面，各组之间无显著差异。
结论
在围产期护理良好的情况下，极高产次似乎并非不良围产期结局的独立危险因素。
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