Vapinov B, Tsankova M, Velev R, Georgiev S
Akush Ginekol (Sofiia). 2001;40(4):42-4.
To evaluated and dilated possibilities of prophylaxis and treatment of agent Klioton D in pregnant women.
164 women were evaluated for 1.5 year period between 12 and 40 gest. week. The first group of prophylactic usage was consisted of 118 women, divided in two groups: prophylaxis before cerclage--33 women, between 12 and 20 gest. week, and prophylaxis before delivery--85 cases. The second group was therapeutic usage in 46 women between 16 and 34 gest. week.
Microbiologically superiority of unspecific bacterial agents was proved, mixed bacterial aerobic-anaerobic flora was dominated. More common bacterial vaginosis and candidosis were noted. In therapeutic group 80% were cured. The rate of subjective complaints in two groups was evaluated. Complications after delivery were 0.04%. Complications after cerclage weren't noted.
Microbiological type find in pregnant women and good prophylactic and the therapeutic results make Klion D as appropriate therapeutic agent before cerclage, delivery, in imminent abortions and premature labors.
评估并拓展Klioton D制剂在孕妇预防和治疗方面的可能性。
在164名妊娠12至40周的女性中进行了为期1.5年的评估。预防性使用的第一组包括118名女性，分为两组：宫颈环扎术前预防——33名女性，妊娠12至20周；分娩前预防——85例。第二组为46名妊娠16至34周女性的治疗性使用。
证实了非特异性细菌制剂在微生物学上的优势，混合需氧-厌氧菌群占主导。观察到更常见的细菌性阴道病和念珠菌病。治疗组80%治愈。评估了两组的主观症状发生率。分娩后并发症为0.04%。未观察到宫颈环扎术后并发症。
在孕妇中发现的微生物类型以及良好的预防和治疗效果使Klioton D成为宫颈环扎术、分娩、先兆流产和早产时合适的治疗药物。
