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小鼠升结肠上皮细胞内质网的一种异常改变。

An unusual modification of endoplasmic reticulum in epithelial cells of the mouse ascending colon.

作者信息

Michaels J E

出版信息

Anat Rec. 1975 Sep;183(1):27-38. doi: 10.1002/ar.1091830104.

DOI:10.1002/ar.1091830104
PMID:1180397
Abstract

A rarely occurring structure that is apparently a modification of endoplasmic reticulum was observed in the epithelial cells of the ascending colon of the mouse. The structure consists of a stack of 3 to 15 parallel cisterna-like elements separated by about 67 nm. The stacked cisternae usually are located adjacent to the basal end of the nucleus or in the region between nucleus and basal cell membrane. Top and bottom cisternae of many of the stacks have patent lumens and their outer membranes are lined by ribosomes. Most frequently, middle cisternae have attenuated lumens in their central regions. In some instances the width of the cisternal lumens is similar throughout. Closely apposed pairs of cisternae also occur. Some stacks have a concentric configuration. The intercisternal space contains tightly packed vesicles (38 nm) arranged in a hexagonal array. Many of the vesicles are connected to the membranes of the cisternae by stalk-like projections. The vesicles also occur between the nuclear envelope and the adjacent parallel cisternae. Mitochondria are situated close to each stack.

摘要

在小鼠升结肠的上皮细胞中观察到一种罕见的结构,它显然是内质网的一种变体。该结构由3至15个平行的池状元件堆叠而成,间隔约67纳米。堆叠的池通常位于细胞核基部末端附近或细胞核与基底细胞膜之间的区域。许多堆叠的顶部和底部池具有开放的腔,其外膜排列有核糖体。最常见的是,中间池在其中心区域的腔变窄。在某些情况下,整个池腔的宽度相似。也会出现紧密并列的成对池。一些堆叠具有同心结构。池间空间包含紧密排列成六边形阵列的小泡(38纳米)。许多小泡通过茎状突起与池膜相连。小泡也出现在核膜和相邻平行池之间。线粒体位于每个堆叠附近。

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