Michaels J E
Anat Rec. 1980;196(4):413-20. doi: 10.1002/ar.1091960406.
Tubular structures were observed in surface epithelial cells of mice that had been injected with high dosages of diazo-oxo-norleucine (DON), a glutamine antagonist. The tubules often occurred in bundles which contained a variable number of tubules, often as many as one hundren being present. Within the bundles, the tubules were oriented either randomly or parallel to one another. They measured 25 to 35 nm in diameter with angular or circular profiles and were as long as 1 to 2 micron. In the center of each tubule, a smaller tubule-like component was evident that measured 5 to 7 nm in diameter. With the exception of endoplasmic reticulum, often with attached ribosomes, organelles were excluded from the bundles. Since the tubules and the endoplasmic reticulum occasionally were observed to be continuous, it is suggested that the tubules may originate from this organelle.
在注射了高剂量重氮氧代正亮氨酸（DON，一种谷氨酰胺拮抗剂）的小鼠的表面上皮细胞中观察到了管状结构。这些小管常常成束出现，每束包含数量不等的小管，有时多达一百个。在束内，小管要么随机排列，要么彼此平行。它们的直径为25至35纳米，呈角形或圆形轮廓，长度可达1至2微米。在每个小管的中心，有一个明显的较小的类似小管的成分，其直径为5至7纳米。除了常常附着有核糖体的内质网外，其他细胞器都不在这些束中。由于偶尔观察到小管与内质网是连续的，因此有人提出这些小管可能起源于该细胞器。
