Huff Janice L, Kingsley Karl L, Miller Jennell M, Hoshizaki Deborah K
Department of Biological Sciences, University of Nevada Las Vegas, 4505 Maryland Parkway, Las Vegas, NV 89154-4004, USA.
Mech Dev. 2002 Feb;111(1-2):173-6. doi: 10.1016/s0925-4773(01)00609-8.
The embryonic tracheal system of Drosophila provides an important model for understanding the process of epithelial branching morphogenesis. Here we report the sequence and expression analysis of a novel tracheal gene, named windpipe (wdp). wdp is identical to the predicted gene CG3413 and encodes a transmembrane, leucine-rich repeat family member. wdp transcripts appear abruptly at stage 15 and are restricted to primary tracheal branches that give rise to secondary branches.
果蝇的胚胎气管系统为理解上皮分支形态发生过程提供了一个重要模型。在此，我们报告一个名为气管（wdp）的新型气管基因的序列和表达分析。wdp与预测基因CG3413相同，编码一个跨膜的富含亮氨酸重复序列家族成员。wdp转录本在第15阶段突然出现，并局限于产生次级分支的初级气管分支。
