Zhukov V G, Navashin S M
Antibiotiki. 1975 Sep(9):813-7.
The ultrastructure of staphylococcal cells being in contact with oxacillin, cephaloridin, lincomycin, fusidin or gentamycin was studied with the help of electron microscopy. Differences in the changes of the submicroscopic sturcutre of the cells under the effect of the antibiotics inhibiting the synthesis of the cell walls or protein synthesis were shown. Teh level of the structure changes depended on the drug concentration.
借助电子显微镜研究了与苯唑西林、头孢菌素、林可霉素、夫西地酸或庆大霉素接触的葡萄球菌细胞的超微结构。结果表明,在抑制细胞壁合成或蛋白质合成的抗生素作用下,细胞亚微观结构的变化存在差异。结构变化的程度取决于药物浓度。