使用内毒素评估根尖充填材料的渗漏情况。

Leakage evaluation of root end filling materials using endotoxin.

作者信息

Tang Hong Ming, Torabinejad Mahmoud, Kettering James D

机构信息

Loma Linda University, School of Dentistry, CA 92350, USA.

出版信息

J Endod. 2002 Jan;28(1):5-7. doi: 10.1097/00004770-200201000-00002.

DOI:10.1097/00004770-200201000-00002

PMID:11806652

Abstract

Mineral trioxide aggregate (MTA) has been shown to possess excellent sealing ability when tested with dye, bacteria, and a fluid filtration technique. Endotoxin, a component of the cell wall of Gram-negative bacteria, has been proposed to play a role in the pathogenesis of periradicular lesions. This study used a modified Limulus Amebocyte Lysate test for the presence of endotoxin as a tracer and compared the sealing ability of Super-EBA, IRM, amalgam, and MTA. The results showed that MTA permitted less endotoxin leakage than IRM and amalgam at 1, 2, 6, and 12 wk (p < 0.05), and leaked less than Super-EBA at 2 and 12 wk (p < 0.05).

摘要

当采用染料、细菌和流体过滤技术进行测试时，三氧化矿物凝聚体（MTA）已被证明具有出色的封闭能力。内毒素是革兰氏阴性菌细胞壁的一种成分，有人提出它在根尖周病变的发病机制中起作用。本研究使用改良的鲎试剂检测法来检测内毒素的存在作为示踪剂，并比较了Super-EBA、IRM、银汞合金和MTA的封闭能力。结果显示，在1周、2周、6周和12周时，MTA的内毒素渗漏比IRM和银汞合金少（p<0.05），在2周和12周时，其渗漏比Super-EBA少（p<0.05）。