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[固定及解除固定状态下的骨转换变化。采用45钙和四环素标记的动物实验(作者译)]

[Changes in bone turnover under immobilization and remobilization. Animal experiments using 45Ca and tetracycline labelling (author's transl)].

作者信息

Rosemeyer R, Wallner B

出版信息

Arch Orthop Unfallchir. 1975 Sep 4;83(1):1-8. doi: 10.1007/BF00415976.

DOI:10.1007/BF00415976
PMID:1180759
Abstract

This paper presents an experimental study of rabbits immobilized in plaster of paris casts. By means of Tetracycline and 45Ca-labelling an immobilisation over 12 weeks showed a significant diminuition of bone formation. In the first stages of remobilisation the bone formation was found to be increased and became normally in a later stage. The lower dorsal spine was not sufficiently immobilized in our experiments. Therefore significant changes of bone turnover could not be observed.

摘要

本文介绍了一项对用巴黎石膏固定的兔子进行的实验研究。通过四环素和45钙标记,12周的固定显示骨形成显著减少。在重新活动的最初阶段,发现骨形成增加,并在后期恢复正常。在我们的实验中,下背部脊柱固定不充分。因此,未观察到骨转换的显著变化。

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[Functional adaptation of the bones. Animal experiment studies on rats].[骨骼的功能适应性。对大鼠的动物实验研究]
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The development of osteoporosis. Experimental studies in the adult rat.
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