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[骨骼的功能适应性。对大鼠的动物实验研究]

[Functional adaptation of the bones. Animal experiment studies on rats].

作者信息

Kölln S, Schöttle H, Dallek M, Jungbluth K H

出版信息

Unfallchirurgie. 1983 Jun;9(3):120-4.

PMID:6879837
Abstract

The authors wanted to study the effect of non-physiologic muscular forces on growing rat bones. 35 animals were submitted to a total extirpation of the femur, 40 animals served as control group. They were killed immediately, six, twelve, or 24 weeks later, respectively. The results determined by macroscopic X-ray and fluorescence microscope examination are identical. As opposed to the control tibiae, the tibiae exposed to a greater load showed an increased bone density, increased ventral and lateral annexes, above all within the proximal third, and a torsion apparent in the cross-section. The less loaded tibiae showed a smaller bone density, increased medial and lateral annexes, above all within the proximal third, and a torsion apparent in the cross-section. The results are explained by the varying action of pressure and muscular forces and compared to those achieved by other authors.

摘要

作者们想要研究非生理性肌肉力量对生长中的大鼠骨骼的影响。35只动物接受了股骨完全切除手术,40只动物作为对照组。分别在术后立即、6周、12周或24周将它们处死。通过宏观X射线和荧光显微镜检查得出的结果是一致的。与对照胫骨相比,承受更大负荷的胫骨骨密度增加,腹侧和外侧附件增多,尤其是在近端三分之一处,并且在横截面上有扭转现象。负荷较小的胫骨骨密度较小,内侧和外侧附件增多,尤其是在近端三分之一处,并且在横截面上有扭转现象。这些结果通过压力和肌肉力量的不同作用得到了解释,并与其他作者所取得的结果进行了比较。

相似文献

1
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2
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本文引用的文献

1
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Muscle action, bone rarefaction and bone formation; an experimental study.
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The effects of pressure on epiphyseal growth; the mechanism of plasticity of growing bone.压力对骨骺生长的影响;生长中骨骼可塑性的机制。
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Z Orthop Ihre Grenzgeb. 1973 Oct;111(5):681-705.
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[Changes in bone turnover under immobilization and remobilization. Animal experiments using 45Ca and tetracycline labelling (author's transl)].[固定及解除固定状态下的骨转换变化。采用45钙和四环素标记的动物实验(作者译)]
Arch Orthop Unfallchir. 1975 Sep 4;83(1):1-8. doi: 10.1007/BF00415976.
7
Is the biomechanical principle of 'antagonistic compensation' valid also on the genetic level?
Acta Anat (Basel). 1977;97(2):175-9. doi: 10.1159/000144731.