Shimazaki Rie, Ueyama Hidetsugu, Mori Toshio, Mori Miyuki, Fujimoto Shin, Kumamoto Toshihide, Tsuda Tomiyasu
Third Department of Internal Medicine, Oita Medical University, Hasama 1-1, 879-5593, Oita, Japan.
J Neurol Sci. 2002 Feb 15;194(1):55-8. doi: 10.1016/s0022-510x(01)00675-x.
We described two patients with chronic sensory neuronopathy who had anti-HTLV-I antibody in serum and cerebrospinal fluid but no signs of myelopathy. A sural nerve specimen revealed severe degeneration of myelinated and unmyelinated axons. The second patient had subclinical Sjögren's syndrome suggestive of a possible link among human T-cell lymphotropic virus type I (HTLV-I), Sjögren's syndrome and sensory neuronopathy, respectively. The broad spectrum of neurologic disorders associated with HTLV-I infection now would include chronic sensory neuronopathy.
我们描述了两名患有慢性感觉神经元病的患者，他们的血清和脑脊液中存在抗人类嗜T淋巴细胞病毒I型（HTLV-I）抗体，但没有脊髓病的迹象。腓肠神经标本显示有髓和无髓轴突严重变性。第二名患者患有亚临床干燥综合征，提示HTLV-I、干燥综合征和感觉神经元病之间可能存在联系。现在，与HTLV-I感染相关的广泛神经系统疾病将包括慢性感觉神经元病。
