Laloux P, Brucher J M, Guerit J M, Sindic C J, Laterre E C
Department of Neurology, UCL Mont-Godinne Hospital, Yvoir, Belgium.
J Neurol. 1988 Jul;235(6):352-4. doi: 10.1007/BF00314231.
Sensory subacute neuropathies associated with sicca syndrome without any systemic involvement have been reported rarely. A sixth case is described with what appears to be the first report of muscle and nerve biopsy findings. The histological studies revealed axonal degeneration without vasculitis in the sural nerve, and a slight denervation process and a discrete myositis in the gastrocnemius muscle, reflecting a subtle systemic disorder. The clinical course of a long-standing subacute sensory neuropathy, the biopsy-documented axonal degeneration, and the neurophysiological findings suggest involvement of the dorsal root ganglia.
与干燥综合征相关且无任何全身受累的感觉性亚急性神经病变鲜有报道。本文描述了第六例病例，并首次报告了肌肉和神经活检结果。组织学研究显示，腓肠神经存在轴索性变性但无血管炎，腓肠肌有轻微失神经支配过程及散在性肌炎，提示存在一种隐匿的全身性疾病。长期存在的亚急性感觉性神经病变的临床病程、活检证实的轴索性变性以及神经生理学检查结果提示背根神经节受累。
