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First trial of the HIV-1 vaccine in Africa: Ugandan experience.

作者信息

Mugerwa Roy D, Kaleebu Pontiano, Mugyenyi Peter, Katongole-Mbidde Edward, Hom David L, Byaruhanga Rose, Salata Robert A, Ellner Jerrold J

机构信息

Department of Medicine, Makerere University Medical School, Kampala, Uganda.

出版信息

BMJ. 2002 Jan 26;324(7331):226-9. doi: 10.1136/bmj.324.7331.226.

DOI:10.1136/bmj.324.7331.226
PMID:11809648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1122137/
Abstract
摘要

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Developing AIDS vaccine trials educational programs in Uganda.在乌干达开展艾滋病疫苗试验教育项目。
J Acquir Immune Defic Syndr. 2001 Feb 1;26(2):176-81. doi: 10.1097/00042560-200102010-00012.
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Human immunodeficiency virus vaccine development in developing countries: are efficacy trials feasible?发展中国家的人类免疫缺陷病毒疫苗研发:疗效试验可行吗?
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Accelerating the development and future availability of HIV-1 vaccines: why, when, where, and how?加速HIV-1疫苗的研发及未来可得性:为何、何时、何地以及如何?
Lancet. 2000 Jun 10;355(9220):2061-6. doi: 10.1016/S0140-6736(00)02360-6.
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Safety and immunogenicity of a live recombinant canarypox virus expressing HIV type 1 gp120 MN MN tm/gag/protease LAI (ALVAC-HIV, vCP205) followed by a p24E-V3 MN synthetic peptide (CLTB-36) administered in healthy volunteers at low risk for HIV infection. AGIS Group and L'Agence Nationale de Recherches sur Le Sida.在低感染HIV风险的健康志愿者中,表达1型HIV gp120 MN MN tm/gag/蛋白酶LAI(ALVAC-HIV,vCP205)的重组金丝雀痘病毒活疫苗,随后接种p24E-V3 MN合成肽(CLTB-36)的安全性和免疫原性。AGIS集团和法国国家艾滋病研究机构。
AIDS Res Hum Retroviruses. 1999 May 1;15(7):633-45. doi: 10.1089/088922299310935.
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HIV vaccine development for the world: an idea whose time has come?
AIDS Res Hum Retroviruses. 1998 Oct;14 Suppl 3:S191-6.
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Bioethics and local circumstances.
Science. 1998 Jan 9;279(5348):155. doi: 10.1126/science.279.5348.155a.
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HIV-1 risk and vaccine acceptability in the Ugandan military.
J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Aug 15;15(5):375-80. doi: 10.1097/00042560-199708150-00008.
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Ethical, behavioral, and social aspects of HIV vaccine trials in developing countries.发展中国家艾滋病毒疫苗试验的伦理、行为和社会方面。
JAMA. 1994 Jan 26;271(4):295-301.
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Behavioral research contributions to planning and conducting HIV vaccine efficacy studies.行为研究对规划和开展HIV疫苗效力研究的贡献。
AIDS Res Hum Retroviruses. 1994;10 Suppl 2:S277-80.
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The safety and use of canarypox vectored vaccines.金丝雀痘病毒载体疫苗的安全性及应用
Dev Biol Stand. 1995;84:165-70.