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一名患有大动脉炎、系统性红斑狼疮和抗磷脂抗体综合征的年轻患者发生与颈动脉夹层相关的卒中。

Stroke related to carotid artery dissection in a young patient with Takayasu arteritis, systemic lupus erythematosus and antiphospholipid antibody syndrome.

作者信息

Caso V, Paciaroni M, Parnetti L, Cardaioli G, Biscarini L, Acciarini A E, Rubino S, Gallai V

机构信息

Stroke Unit, Department of Neuroscience, Unit of Internal Medicine and Oncological Sciences, University of Perugia, Italy.

出版信息

Cerebrovasc Dis. 2002;13(1):67-9. doi: 10.1159/000047749.

Abstract

Autoimmune diseases are rarely the cause of stroke even in the young age group in association with cervical artery dissection and collagen vascular diseases. Takayasu arteritis is a chronic, idiopathic, inflammatory disease that primarily affects large vessels, such as the aorta and its main branches. Takayasu arteritis rarely coexists with systemic lupus erythematosus, and only few cases have been reported in association with the presence of antiphospholipid antibodies. We describe a young patient with right internal carotid artery dissection and subsequent stroke who presented with all three syndromes. Although this patient met the diagnostic criteria for each syndrome, systemic lupus erythematosus, Takayasu arteritis and the antiphospholipid antibody syndrome, it remains unlikely that the three disorders are not related. We suggest a single disimmune disorder may have led to carotid artery dissection.

摘要

自身免疫性疾病即使在与颈动脉夹层和胶原血管疾病相关的年轻人群中也很少是中风的原因。高安动脉炎是一种慢性、特发性炎症性疾病,主要影响大血管,如主动脉及其主要分支。高安动脉炎很少与系统性红斑狼疮共存,仅有少数病例报道与抗磷脂抗体的存在有关。我们描述了一名患有右颈内动脉夹层并随后发生中风的年轻患者,其同时出现了这三种综合征。尽管该患者符合每种综合征的诊断标准,即系统性红斑狼疮、高安动脉炎和抗磷脂抗体综合征,但这三种疾病不太可能没有关联。我们认为可能是单一的免疫失调性疾病导致了颈动脉夹层。

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