Amaechi Bennett T, Higham Susan M
University of Texas Health Science Center at San Antonio, Department of Community Dentistry, Cariology Group, San Antonio, Texas 78229, USA.
J Biomed Opt. 2002 Jan;7(1):7-13. doi: 10.1117/1.1427044.
Current dental diagnostic methods can detect caries but cannot quantify the mineral status of a lesion. Quantitative light-induced fluorescence (QLF) measures the percentage of fluorescence change of demineralized enamel with respect to surrounding sound enamel, and relates it directly to the amount of mineral lost during demineralization. Development of caries-like lesions and subsequent remineralization of the lesions were monitored by QLF. The results showed that the percentage of fluorescence change (Delta Q) increased linearly with the demineralization time and decreased with increased remineralization time. Stained teeth were whitened with a bleaching agent and the change in stain intensity (Delta E) was quantified using QLF. The results showed that Delta E decreased linearly as the tooth regained its natural color. Factors that might affect the use of QLF to detect and quantify caries were also examined. It was concluded that QLF could be used to detect and longitudinally monitor the progression or remineralization of incipient caries, however lesion detection may be limited by the presence of saliva or plaque and enhanced by staining. The change in shade of discolored teeth by whitening agents could be quantitatively measured by QLF.
目前的牙科诊断方法能够检测出龋齿,但无法量化病变部位的矿物质状态。定量光诱导荧光(QLF)测量脱矿釉质相对于周围健康釉质的荧光变化百分比,并将其直接与脱矿过程中损失的矿物质含量相关联。通过QLF监测龋样病变的发展以及病变随后的再矿化情况。结果表明,荧光变化百分比(ΔQ)随脱矿时间呈线性增加,随再矿化时间增加而降低。用漂白剂使染色牙齿变白,并使用QLF对染色强度变化(ΔE)进行量化。结果表明,随着牙齿恢复其自然颜色,ΔE呈线性下降。还研究了可能影响使用QLF检测和量化龋齿的因素。得出的结论是,QLF可用于检测和纵向监测早期龋齿的进展或再矿化情况,然而病变检测可能会受到唾液或牙菌斑的影响,而染色则会增强检测效果。美白剂导致的变色牙齿色度变化可通过QLF进行定量测量。