Zwar Nicholas, Henderson Joan, Britt Helena, McGeechan Kevin, Yeo Guan
Department of General Practice, University of New South Wales, Australia.
Fam Pract. 2002 Feb;19(1):12-7. doi: 10.1093/fampra/19.1.12.
The extent of use of antibiotics for upper respiratory tract infection (URTI) prompted a previous study of an educational intervention based on prescriber feedback and management guidelines. This study demonstrated a reduction in antibiotic prescribing for URTI and a more appropriate choice of antibiotic for tonsillitis/streptococcal pharyngitis. There are few long-term follow-up studies of educational programmes of this kind.
This follow-up study aimed to examine if the reduction in antibiotic prescribing observed in the intervention group of the original study remained present after 5 years, and how the prescribing behaviour of the GPs involved in the follow-up differed from a large national survey of GP prescribing.
Attempts were made to contact the 157 GPs involved in the original study. Of these, 121 were both located and currently working in general practice. Ninety-six consented to take part and, of these, 79 completed a morbidity and treatment survey of 100 patient encounters (response rate 65.3%).
The intervention group (n = 37) maintained their pattern of prescribing of antibiotics for URTI and choice of antibiotic for tonsillitis/streptococcal pharyngitis, with no significant change between the completion of the original study and the 5-year follow-up. The control group (n = 42) showed a downward trend in antibiotic prescribing for URTI, with the effect that no significant differences remained between groups at the 5-year follow-up. At the 5-year follow-up, both groups prescribed significantly fewer antibiotics for URTI and showed greater adherence to prescribing guidelines for tonsillitis/streptococcal pharyngitis than participants in a large national GP survey (n = 984).
This study demonstrated maintenance of prescribing behaviour in the intervention group in the long term. However, the changes in prescribing observed in the control group and the power limitations of the study make it uncertain whether this was the result of a sustained effect of the educational intervention. The differences in both groups from the large national GP survey suggest that other influences on prescribing (such as participation in vocational training for general practice) were also having an important effect.
上呼吸道感染(URTI)抗生素的使用范围促使之前开展了一项基于开处方者反馈和管理指南的教育干预研究。该研究表明,URTI的抗生素处方量有所减少,且对于扁桃体炎/链球菌性咽炎,抗生素的选择更为恰当。此类教育项目的长期随访研究较少。
这项随访研究旨在检验原研究干预组中观察到的抗生素处方量减少情况在5年后是否依然存在,以及参与随访的全科医生(GP)的处方行为与一项大型全国性GP处方调查相比有何不同。
研究人员试图联系参与原研究的157名GP。其中,121名已找到且目前仍在从事全科医疗工作。96名同意参与,其中79名完成了100次患者诊疗的发病率和治疗情况调查(回复率65.3%)。
干预组(n = 37)维持了其针对URTI的抗生素处方模式以及针对扁桃体炎/链球菌性咽炎的抗生素选择模式,从原研究结束到5年随访期间无显著变化。对照组(n = 42)显示URTI的抗生素处方量呈下降趋势,结果在5年随访时两组之间无显著差异。在5年随访时,与一项大型全国性GP调查(n = 984)的参与者相比,两组针对URTI开具的抗生素均显著减少,且在扁桃体炎/链球菌性咽炎的处方指南遵循方面表现更佳。
本研究表明干预组的处方行为长期保持稳定。然而,对照组中观察到的处方变化以及研究的效能限制使得不确定这是否是教育干预持续作用的结果。两组与大型全国性GP调查的差异表明,对处方的其他影响因素(如参与全科医疗职业培训)也发挥着重要作用。