Akkerman Annemiek E, Kuyvenhoven Marijke M, van der Wouden Johannes C, Verheij Theo J M
Julius Center for Health Sciences and Primary Care, Rotterdam, The Netherlands.
Br J Gen Pract. 2005 Feb;55(511):114-8.
Due to clinical and non-clinical factors, considerable variation exists in the prescribing of antibiotics for respiratory tract infections (RTIs) by GPs based in the Netherlands.
To assess, in patients with RTIs in Dutch general practice: the prescribing rates of antibiotics; the relationship between GP characteristics and antibiotic prescribing; and the type of antibiotics prescribed.
Descriptive and prognostic.
Eighty-four GPs in the middle region of the Netherlands.
All patient consultations for RTIs were registered by 84 GPs during 3 weeks in autumn and winter 2001 and 2002. In addition, all GPs completed a questionnaire related to individual and practice characteristics.
The mean proportion of consultations in which GPs prescribed antibiotics was 33% (95% CI = 29 to 35%) of all RTIs. This proportion varied from 21% for patients with upper RTIs or an exacerbation of asthma/COPD, to about 70% when patients had sinusitis-like complaints or pneumonia. Amoxycillin and doxycycline were the most frequently prescribed antibiotics, while 17% of the antibiotics prescribed were macrolides. Multiple linear regression analysis showed that the longer GPs had practised, the more frequently they prescribed antibiotics, especially in combination with relatively little knowledge about RTIs or the less time GPs felt they had available per patient. The final model, with seven factors, explained 29% of the variance of antibiotic prescribing.
The prescribing behaviour of Dutch GPs might be improved with regard to choice of type and indication of antibiotics.
由于临床和非临床因素,荷兰的全科医生在开具呼吸道感染(RTIs)抗生素处方方面存在很大差异。
评估荷兰全科医疗中患有RTIs的患者:抗生素的处方率;全科医生特征与抗生素处方之间的关系;以及所开具抗生素的类型。
描述性和预后性。
荷兰中部地区的84名全科医生。
84名全科医生在2001年和2002年秋冬的3周内记录了所有因RTIs进行的患者会诊。此外,所有全科医生都填写了一份与个人和执业特征相关的问卷。
在所有RTIs会诊中,全科医生开具抗生素的平均比例为33%(95%置信区间=29%至35%)。这一比例在上呼吸道感染或哮喘/慢性阻塞性肺疾病加重患者中为21%,而在患有鼻窦炎样症状或肺炎的患者中约为70%。阿莫西林和多西环素是最常开具的抗生素,而所开具抗生素中有17%是大环内酯类。多元线性回归分析表明,全科医生执业时间越长,开具抗生素的频率越高,尤其是在对RTIs了解相对较少或感觉每位患者可用时间较少的情况下。包含七个因素的最终模型解释了抗生素处方差异的29%。
荷兰全科医生在抗生素类型选择和适应症方面的处方行为可能需要改进。