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本文引用的文献

1
Effectiveness of a multiple intervention to reduce antibiotic prescribing for respiratory tract symptoms in primary care: randomised controlled trial.在初级保健中减少呼吸道症状抗生素处方的多重干预措施的有效性:随机对照试验
BMJ. 2004 Aug 21;329(7463):431. doi: 10.1136/bmj.38182.591238.EB. Epub 2004 Aug 5.
2
Outpatient antibiotic prescriptions from 1992 to 2001 in the Netherlands.1992年至2001年荷兰门诊抗生素处方情况。
J Antimicrob Chemother. 2003 Oct;52(4):675-8. doi: 10.1093/jac/dkg412. Epub 2003 Sep 1.
3
How to change clinical behaviour: no answers yet.如何改变临床行为:尚无答案。
Br J Gen Pract. 2003 Apr;53(489):266-7.
4
Systematic review of scope and quality of electronic patient record data in primary care.基层医疗中电子病历数据范围与质量的系统评价
BMJ. 2003 May 17;326(7398):1070. doi: 10.1136/bmj.326.7398.1070.
5
Changing use of antibiotics in community-based outpatient practice, 1991-1999.1991 - 1999年社区门诊实践中抗生素使用情况的变化
Ann Intern Med. 2003 Apr 1;138(7):525-33. doi: 10.7326/0003-4819-138-7-200304010-00008.
6
Antibiotic use and the prevalence of antibiotic resistance in bacteria from healthy volunteers in the dutch community.荷兰社区健康志愿者体内细菌的抗生素使用情况及抗生素耐药性流行情况
Infection. 2003 Jan;31(1):9-14. doi: 10.1007/s15010-002-3035-8.
7
Why do general practitioners prescribe antibiotics for sore throat? Grounded theory interview study.全科医生为何为咽喉痛开具抗生素?扎根理论访谈研究。
BMJ. 2003 Jan 18;326(7381):138. doi: 10.1136/bmj.326.7381.138.
8
Antibiotics for coughing in general practice: a questionnaire study to quantify and condense the reasons for prescribing.全科医疗中治疗咳嗽的抗生素使用情况:一项旨在量化并归纳用药原因的问卷调查研究
BMC Fam Pract. 2002 Sep 9;3:16. doi: 10.1186/1471-2296-3-16.
9
Influencing antibiotic prescribing by prescriber feedback and management guidelines: a 5-year follow-up.通过开具处方者反馈和管理指南影响抗生素处方:一项5年随访研究
Fam Pract. 2002 Feb;19(1):12-7. doi: 10.1093/fampra/19.1.12.
10
Antibiotic use in acute respiratory infections and the ways patients pressure physicians for a prescription.急性呼吸道感染中抗生素的使用以及患者向医生施压开具处方的方式。
J Fam Pract. 2001 Oct;50(10):853-8.

全科医生针对呼吸道感染开具抗生素的情况:管理与开处方者特征

Prescribing antibiotics for respiratory tract infections by GPs: management and prescriber characteristics.

作者信息

Akkerman Annemiek E, Kuyvenhoven Marijke M, van der Wouden Johannes C, Verheij Theo J M

机构信息

Julius Center for Health Sciences and Primary Care, Rotterdam, The Netherlands.

出版信息

Br J Gen Pract. 2005 Feb;55(511):114-8.

PMID:15720932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1463185/
Abstract

BACKGROUND

Due to clinical and non-clinical factors, considerable variation exists in the prescribing of antibiotics for respiratory tract infections (RTIs) by GPs based in the Netherlands.

AIM

To assess, in patients with RTIs in Dutch general practice: the prescribing rates of antibiotics; the relationship between GP characteristics and antibiotic prescribing; and the type of antibiotics prescribed.

DESIGN OF STUDY

Descriptive and prognostic.

SETTING

Eighty-four GPs in the middle region of the Netherlands.

METHOD

All patient consultations for RTIs were registered by 84 GPs during 3 weeks in autumn and winter 2001 and 2002. In addition, all GPs completed a questionnaire related to individual and practice characteristics.

RESULTS

The mean proportion of consultations in which GPs prescribed antibiotics was 33% (95% CI = 29 to 35%) of all RTIs. This proportion varied from 21% for patients with upper RTIs or an exacerbation of asthma/COPD, to about 70% when patients had sinusitis-like complaints or pneumonia. Amoxycillin and doxycycline were the most frequently prescribed antibiotics, while 17% of the antibiotics prescribed were macrolides. Multiple linear regression analysis showed that the longer GPs had practised, the more frequently they prescribed antibiotics, especially in combination with relatively little knowledge about RTIs or the less time GPs felt they had available per patient. The final model, with seven factors, explained 29% of the variance of antibiotic prescribing.

CONCLUSION

The prescribing behaviour of Dutch GPs might be improved with regard to choice of type and indication of antibiotics.

摘要

背景

由于临床和非临床因素,荷兰的全科医生在开具呼吸道感染(RTIs)抗生素处方方面存在很大差异。

目的

评估荷兰全科医疗中患有RTIs的患者:抗生素的处方率;全科医生特征与抗生素处方之间的关系;以及所开具抗生素的类型。

研究设计

描述性和预后性。

研究地点

荷兰中部地区的84名全科医生。

方法

84名全科医生在2001年和2002年秋冬的3周内记录了所有因RTIs进行的患者会诊。此外,所有全科医生都填写了一份与个人和执业特征相关的问卷。

结果

在所有RTIs会诊中,全科医生开具抗生素的平均比例为33%(95%置信区间=29%至35%)。这一比例在上呼吸道感染或哮喘/慢性阻塞性肺疾病加重患者中为21%,而在患有鼻窦炎样症状或肺炎的患者中约为70%。阿莫西林和多西环素是最常开具的抗生素,而所开具抗生素中有17%是大环内酯类。多元线性回归分析表明,全科医生执业时间越长,开具抗生素的频率越高,尤其是在对RTIs了解相对较少或感觉每位患者可用时间较少的情况下。包含七个因素的最终模型解释了抗生素处方差异的29%。

结论

荷兰全科医生在抗生素类型选择和适应症方面的处方行为可能需要改进。