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[正常及兴奋状态下大脑各部位的磷脂和凝血致活酶]

[Phospholipids and thromboplastins in various sections of the brain normally and in excitation states].

作者信息

Pogosbekova S D, Ovakimian S S, Ovsepian L M, Karagezian K G

出版信息

Biull Eksp Biol Med. 1975 Aug;80(8):6-8.

PMID:1182306
Abstract

The level of the neutral and acid phospholipids and thromboplastic activity of various portions of the rabbit brain were studied under normal conditions and following adrenaline stimulation. The level of total phospholipids, neutral phospholipids, and the ratio of neutral to acid phospholipids, thromboplastic activity and its increase following incubation of homogenates of the brain tissue of normal and adrenaline-treated animals were found to be distributed in the following descending order: the medulla oblongata, cerebellum, cerebral hemispheres. Adrenaline decreased the thromboplastic activity and induced changes in the neutral and acid phospholipid levels. The role of phospholipids in the biosynthesis of various components of the blood clotting and anticoagulant systems are discussed.

摘要

研究了正常条件下以及肾上腺素刺激后兔脑各部分的中性和酸性磷脂水平及凝血活性。发现正常动物和肾上腺素处理动物脑组织匀浆孵育后的总磷脂水平、中性磷脂水平、中性与酸性磷脂的比例、凝血活性及其增加情况按以下降序分布:延髓、小脑、大脑半球。肾上腺素降低了凝血活性,并引起中性和酸性磷脂水平的变化。讨论了磷脂在血液凝固和抗凝系统各成分生物合成中的作用。

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